With the rapid development and complex challenges of chemical substances, new drug synthesis pathways are usually the most effective.52562-50-2,5-Methyl-1H-indole-3-carbaldehyde,as a common compound, the synthetic route is as follows.
52562-50-2, General procedure: An equimolar mixture of Gewald adducts (5CN, 6CN, 7CN and 8CN) and substituted indole-carboxaldehydes in absolute ethanol with 0.5 mL of acetic acid was stirred under room temperature for 24 hs. Water was addedand the solid that precipitated out was filtered under vacuum, washed with water, dried and recrystallized from absolute ethanol (Scheme 1) according previously methodology [20].
As the paragraph descriping shows that 52562-50-2 is playing an increasingly important role.
Reference£º
Article; Felix, Mayara B.; de Souza, Edson R.; de Lima, Maria do C.A.; Frade, Daiana Karla G.; Serafim, Vanessa de L.; Rodrigues, Klinger Antonio da F.; Neris, Patricia Lima do N.; Ribeiro, Frederico F.; Scotti, Luciana; Scotti, Marcus T.; de Aquino, Thiago M.; Mendonca Junior, Francisco Jaime B.; de Oliveira, Marcia R.; Bioorganic and Medicinal Chemistry; vol. 24; 18; (2016); p. 3972 – 3977;,
Indole alkaloid derivatives as building blocks of natural products from?Bacillus thuringiensis?and?Bacillus velezensis?and their antibacterial and antifungal activity study
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