81224-16-0, 7-Bromo-4-methoxy-1H-indole is a indole-building-block compound, ?involved in a variety of chemical synthesis. Rlated chemical reaction is continuously updated
81224-16-0, An oven-dried screw cap test tube was charged with a magnetic stir bar, CuCN (152.4 mg, 0.8mmol), then 34 (6.8 g, Y = 70.1%) in DMF (75 mL) was added into the tube. The reaction mixture wasstirred at 140 C overnight. After cooled down to room temperature, the resulting solution wasfiltered through Celite. The filtrate was diluted with ethyl acetate (100 mL) and washed withsaturated NaHCO3 solution (30 mL), water (30 mL) and brine (30 mL). The organic phase was driedover anhydrous Na2SO4, filtered and concentrated under reduced pressure. The residue was purifiedby silica gel column (petroleum ether/ethyl acetate = 1:1, v/v) to give 35 as a yellow solid (3.4 g, yield %). LC-MS (ESI): m/z [M + 1]+ = 173.10.
81224-16-0 7-Bromo-4-methoxy-1H-indole 3695499, aindole-building-block compound, is more and more widely used in various fields.
Reference£º
Article; Meuser, Megan E.; Rashad, Adel A.; Ozorowski, Gabriel; Dick, Alexej; Ward, Andrew B.; Cocklin, Simon; Molecules; vol. 24; 8; (2019);,
Indole alkaloid derivatives as building blocks of natural products from?Bacillus thuringiensis?and?Bacillus velezensis?and their antibacterial and antifungal activity study
Preparation of Indole Containing Building Blocks for the Regiospecific Construction of Indole Appended Pyrazoles and Pyrroles