Some scientific research about 4-Bromo-7-azaindole

Note that a catalyst decreases the activation energy for both the forward and the reverse reactions and hence accelerates both the forward and the reverse reactions.Computed Properties of C7H5BrN2, you can also check out more blogs about348640-06-2

Chemistry is traditionally divided into organic and inorganic chemistry. Computed Properties of C7H5BrN2. The former is the study of compounds containing at least one carbon-hydrogen bonds.In a patent，Which mentioned a new discovery about 348640-06-2

Eight platinum(II) complexes of the general formula cis-[PtCl2(L)2] containing 7-azaindole (L = 7AIH) and its halogeno-derivatives: L = 3-chloro-7-azaindole (3Cl7AIH); 3-bromo-7-azaindole (3Br7AIH); 4-chloro-7-azaindole (4Cl7AIH); 4-bromo-7-azaindole (4Br7AIH); 5-bromo-7-azaindole (5Br7AIH); 3-bromo-4-chloro-7-azaindole (3Br4Cl7AIH) and 5-bromo-3-chloro-7-azaindole (5Br3Cl7AIH) were prepared. Two complexes, cis-[PtCl2(3Br4Cl7AIH)2] (2) and cis-[PtCl2(4Br7AIH)2]·DMF, are reported for the first time. Crystal structure of the latter compound has been determined with X-ray diffraction analysis (space group P43, with a = 14.775(2), c = 41.640(8) A, V = 9090(3) A3 and Z = 16). For all of these complexes, formation of the cis isomers in the solid state was confirmed by experimental vibrational (IR and Raman) spectroscopy combined with DFT calculations. A complete assignment of the IR and Raman spectra was made on the basis of the calculated potential energy distribution (PED). Stability of complex (2) in DMSO solution was investigated by FT-IR (ATR) spectroscopy. The in vitro antiproliferative activity of cis-[PtCl2(3Br4Cl7AIH)2], cis-[PtCl2(3Cl7AIH)2] and cis-[PtCl2(3Br7AIH)2] was evaluated on selected human cancer cell lines and towards normal mouse fibroblast cell line (BALB/3T3). All complexes are more toxic than cisplatin against Es-2 (ovarian cancer), LNCaP (prostate adenocarcinoma) and MCF7 (breast cancer). Moreover, complex (2) is significantly more active than the other complexes on A549 (lung carcinoma, IC50 = 3.9 muM). However, the three investigated Pt(II) complexes with 7-azaindoles have revealed higher cytotoxicity against a normal cell line (BALB/3T3), in comparison to cisplatin.

Note that a catalyst decreases the activation energy for both the forward and the reverse reactions and hence accelerates both the forward and the reverse reactions.Computed Properties of C7H5BrN2, you can also check out more blogs about348640-06-2

Reference：
Indole alkaloid derivatives as building blocks of natural products from Bacillus thuringiensis and Bacillus velezensis and their antibacterial and antifungal activity study,
Preparation of Indole Containing Building Blocks for the Regiospecific Construction of Indole Appended Pyrazoles and Pyrroles