In an article, author is Zhao, Shufang, once mentioned the application of 36322-90-4, Safety of 4-Hydroxy-2-methyl-N-(pyridin-2-yl)-2H-benzo[e][1,2]thiazine-3-carboxamide 1,1-dioxide, Name is 4-Hydroxy-2-methyl-N-(pyridin-2-yl)-2H-benzo[e][1,2]thiazine-3-carboxamide 1,1-dioxide, molecular formula is C15H13N3O4S, molecular weight is 331.3464, MDL number is MFCD00057317, category is indole-building-block. Now introduce a scientific discovery about this category.
The Pd(II) catalyzed direct C2 alkynylation of indoles bearing N-2-pyrimidyl or N-2-pyridinyl moiety as a site-specific directing group was developed with alkynyl halide. A highly regioselective manner can be achieved on a range of indole substrates with excellent functional group tolerance.
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Reference:
Indole alkaloid derivatives as building blocks of natural products from Bacillus thuringiensis and Bacillus velezensis and their antibacterial and antifungal activity study,
,Preparation of Indole Containing Building Blocks for the Regiospecific Construction of Indole Appended Pyrazoles and Pyrroles