Some scientific research about 5-Bromo-3-(2-(pyrrolidin-1-yl)ethyl)-1H-indole

Enzymes are biological catalysts that produce large increases in reaction rates and tend to be specific for certain reactants and products. I hope my blog about is helpful to your research. 17274-68-9

Chemistry is the experimental and theoretical study of materials on their properties at both the macroscopic and microscopic levels.In a patent£¬Which mentioned a new discovery about 17274-68-9, molcular formula is C14H17BrN2, introducing its new discovery. , 17274-68-9

5-CYCLO INDOLE COMPOUNDS

Described herein are compounds selective for a 5-HT 1D-like receptor, which have the general formula: STR1 wherein A is selected from a six-membered, non-aromatic, optionally substituted carbocycle and a six-membered, non-aromatic, optionally substituted heterocycle having one or two heteroatoms selected from O, S, SO, SO 2 and N 4 ;< P>

R 1 is selected from H and OH;< P>

n is 0 or 1 as permited by chemical structure;

< P>R 2 is selected from CR 5 CR 6 CH. sub.2 NR 7 R 8 or a group of formula II, III or IV: STR2 R. sup.3 is selected from H and benzoyl; R 4 is selected from H, loweralkyl, benzyl, loweralkylcarbonyl, loweralkylaminocarbonyl, loweralkylaminothiocarbonyl, loweralkanoyl, loweralkylaminoimide and loweralkoxy-substituted loweralkylene;

R 5 and R. sup.6 are independently selected from H, loweralkoxy and hydroxy;

R 7 and R. sup.8 are independently selected from H and loweralkyl or R 7 and R. sup.8 form an alkylene bridge which, together with the nitrogen atom to which they are attached, creates an optionally substituted 3-to 6-membered ring;

denotes a single or double bond; and< P>

R. sup.9, R. sup.10 and R. sup.11 are independently selected from H and loweralkyl.

Also described is the use of these compounds as pharmaceuticals to treat indications where stimulation of a 5-HT 1D-like receptor is implicated, such as migraine.

Enzymes are biological catalysts that produce large increases in reaction rates and tend to be specific for certain reactants and products. I hope my blog about is helpful to your research. 17274-68-9

Reference£º
Indole alkaloid derivatives as building blocks of natural products from?Bacillus thuringiensis?and?Bacillus velezensis?and their antibacterial and antifungal activity study,
Preparation of Indole Containing Building Blocks for the Regiospecific Construction of Indole Appended Pyrazoles and Pyrroles