A catalyst don’t appear in the overall stoichiometry of the reaction it catalyzes, but it must appear in at least one of the elementary reactions in the mechanism for the catalyzed reaction. 5995-86-8, Name is 3,4,5-Trihydroxybenzoic acid hydrate, molecular formula is C7H8O6. In an article, author is Deng, Chao,once mentioned of 5995-86-8, COA of Formula: https://www.ambeed.com/products/5995-86-8.html.
Density functional theory calculations were carried out to study the reaction mechanism of the Rh(III)-catalyzed regioselective C-H cyanation of indole and indoline with N-cyano-N-phenyl-para-methylbenzenesulfonamide (NCTS). This mechanism involves four major steps: C-H activation, cyano group insertion, beta-N elimination, and regeneration of active species. How different indole and indoline substrates affect the regioselectivity of C-H bond cyanation has been examined and analyzed in detail. Our calculation results indicate that the regioselectivity of C-H bond cyanation of indole depends on the nucleophilicity of carbon atoms in C-Rh(III) bonds to the cyano group. For indoline, it can be attributed to the different hybridization platforms of the C-H bond activation.
Interested yet? Keep reading other articles of 5995-86-8, you can contact me at any time and look forward to more communication. COA of Formula: https://www.ambeed.com/products/5995-86-8.html.
Reference:
Indole alkaloid derivatives as building blocks of natural products from Bacillus thuringiensis and Bacillus velezensis and their antibacterial and antifungal activity study,
,Preparation of Indole Containing Building Blocks for the Regiospecific Construction of Indole Appended Pyrazoles and Pyrroles