Related Products of 877-03-2, Catalysts are substances that increase the reaction rate of a chemical reaction without being consumed in the process. 877-03-2, Name is 5-Bromo-1H-indole-3-carbaldehyde, molecular formula is C9H6BrNO. In a Article£¬once mentioned of 877-03-2
Synthesis, antitumor evaluation, and molecular docking studies of indole?indazolyl hydrazide?hydrazone derivatives
Abstract: A series of ten novel hydrazide?hydrazones linked indole and indazole moieties were designed and synthesized. All the synthesized compounds were evaluated for their cytotoxicity against four human cancer cell lines (HeLa, MDA-MB-231, MCF-7, and A549). Three of the synthesized compounds showed promising cytotoxicity specifically on some of the tested cell lines with IC50 values ranging between 1.93 and 25.6?muM. Further, one compound was identified as a promising drug lead which showed promising cytotoxicity with IC50 value of 1.93?muM towards MCF-7 breast cancer cell line as compared to the standard drug doxorubicin (IC50 value 0.98?muM). While, all these new compounds showed no cytotoxicity on the normal human embryonic kidney cell line, HEK-293. Graphical abstract: [Figure not available: see fulltext.]
Sometimes chemists are able to propose two or more mechanisms that are consistent with the available data. Related Products of 877-03-2, If a proposed mechanism predicts the wrong experimental rate law, however, the mechanism must be incorrect.Welcome to check out more blogs about 877-03-2, in my other articles.
Reference£º
Indole alkaloid derivatives as building blocks of natural products from?Bacillus thuringiensis?and?Bacillus velezensis?and their antibacterial and antifungal activity study,
Preparation of Indole Containing Building Blocks for the Regiospecific Construction of Indole Appended Pyrazoles and Pyrroles