Reference of 487021-52-3, Catalysts allow a reaction to proceed via a pathway that has a lower activation energy than the uncatalyzed reaction. 487021-52-3, Name is AR-A014418, SMILES is O=C(NC1=NC=C([N+]([O-])=O)S1)NCC2=CC=C(OC)C=C2, belongs to indole-building-block compound. In a article, author is Chen, Wei-Hao, introduce new discover of the category.
Twelve indole alkaloids, including alpha-cyclopiazonic acid (CPA) (1), nine 2-oxo indole CPA derivatives (2-10), and two open-ring indole CPA derivatives (11and12), were isolated from the fermentation broth of a deep-sea derived fungusAspergillussp. SCSIO 41024. Their structures and absolute configurations were elucidated mainly by using extensive NMR spectroscopic, mass spectrometric and single crystal X-ray diffraction analysis. To the best of our knowledge, the crystallographic data of3and7were firstly reported, and the absolute configuration of3was confirmed for the first time by the single crystal X-ray diffraction analysis. Most isolated compounds were tested for their antimicrobial, antitumor and radical scavenging activities. In addition, compounds1,2and11showed moderate antioxidative activity against DPPH with IC(50)values of 190.1, 31.9, 228.4 mu g/mL, respectively.
Reference of 487021-52-3, Because enzymes can increase reaction rates by enormous factors and tend to be very specific, typically producing only a single product in quantitative yield, they are the focus of active research.you can also check out more blogs about 487021-52-3.
Reference:
Indole alkaloid derivatives as building blocks of natural products from Bacillus thuringiensis and Bacillus velezensis and their antibacterial and antifungal activity study,
,Preparation of Indole Containing Building Blocks for the Regiospecific Construction of Indole Appended Pyrazoles and Pyrroles