1074-86-8, 1H-Indole-4-carbaldehyde is a indole-building-block compound, ?involved in a variety of chemical synthesis. Rlated chemical reaction is continuously updated
Sjp3. Synthesis of (E)-N?-(( 1 H-indol-4-yl)methylene)-2-(2-(trifluoromethyl)phenoxy)acetohydrazide: 2-(2-(trifluoromethyl)phenoxy)acetohydrazide (0.2 g, 0.85 mmol) and 1H-indol-4-carbaldehyde (0.13 g, 0.85 mmol) were dissolved in ethanol, followed by stirring at 100 ¡ãC for 16 hours. After the completion of the reaction, the reactionmixture was concentrated under reduced pressure. The concentrate was purified by column chromatography to obtain Compound 192 (0.27 g, 88 percent).?H NMR (400 MHz, DMSO-d6): 11.57-11.33 (m, 2H), 8.43-8.25 (m, 1H), 7.64-7.44 (m, 4H), 7.25-6.96 (m, 6H), 5.37-4.84 (m, 2H)., 1074-86-8
1074-86-8 1H-Indole-4-carbaldehyde 333703, aindole-building-block compound, is more and more widely used in various fields.
Reference£º
Patent; CHONG KUN DANG PHARMACEUTICAL CORP.; INJE UNIVERSITY INDUSTRY-ACADEMIC COOPERATION FOUNDATION; CHOI, HoJin; LEE, JaeWon; LEE, ChangGon; HA, NiNa; SEO, Su Kil; LEE, SunMi; LEE, Song-Min; WO2014/35149; (2014); A1;,
Indole alkaloid derivatives as building blocks of natural products from?Bacillus thuringiensis?and?Bacillus velezensis?and their antibacterial and antifungal activity study
Preparation of Indole Containing Building Blocks for the Regiospecific Construction of Indole Appended Pyrazoles and Pyrroles