14618-45-2, 3-(Trifluoroacetyl)indole is a indole-building-block compound, ?involved in a variety of chemical synthesis. Rlated chemical reaction is continuously updated
General procedure: Diethyl (1-fluoro-1-carbethoxymethyl) phosphonate (1, 2mmol) and 1 ml of CH2Cl2 were placed into a nitrogenflushed round-bottomed flask equipped with magnetic stirring.NaH (2 mmol) was added at room temperature to theabove solution. Then 1 mmol of the trifluoromethyl ketoneor fluoral was added. The progress of the reaction was monitoredby TLC and GC-MS, and after its completion the mixturewas passed through a short silica-gel column withCH2Cl2 as solvent to remove phosphine oxide. The crudeproducts were purified by flash chromatography
14618-45-2, The synthetic route of 14618-45-2 has been constantly updated, and we look forward to future research findings.
Reference：
Article; Landge, Shainaz M.; Roek, Bela Toe; Letters in Organic Chemistry; vol. 11; 5; (2014); p. 374 – 379;,
Indole alkaloid derivatives as building blocks of natural products from?Bacillus thuringiensis?and?Bacillus velezensis?and their antibacterial and antifungal activity study
Preparation of Indole Containing Building Blocks for the Regiospecific Construction of Indole Appended Pyrazoles and Pyrroles