244-76-8, 9H-Pyrido[2,3-b]indole is a indole-building-block compound, ?involved in a variety of chemical synthesis. Rlated chemical reaction is continuously updated
2-necked 250ml flask, the compound (4) (0.6g, 1.23mmol), alpha-carboline (0.45g, 2.71mmol), NaOtBu (0.35g, 3.69mmol) were placed in toluene (100ml) was stirred under nitrogen, and the reaction temperature the temperature was raised to 80 C and reacted for 1 hour. To the resulting solution was added Pd (dba) 2 (0.02g, 0.04mmol), (tert-Bu) 3P (0.01g, 0.06mmol) and allowed to react at 80 C for 1 ~ 2days. Remove salts by filtration of the reaction solution It was. Remove the toluene was evaporated from the solution by filtration, remove the concentrate to the column to obtain the compound (3-10, AnT-DaC3) 0.49g (yield: 60%)
244-76-8, The synthetic route of 244-76-8 has been constantly updated, and we look forward to future research findings.
Reference£º
Patent; WS Co., Ltd; Ko, Byung Soo; Kim, Kyu Sik; Oh, Yu Jin; (52 pag.)KR101528768; (2015); B1;,
Indole alkaloid derivatives as building blocks of natural products from?Bacillus thuringiensis?and?Bacillus velezensis?and their antibacterial and antifungal activity study
Preparation of Indole Containing Building Blocks for the Regiospecific Construction of Indole Appended Pyrazoles and Pyrroles