Some tips on 31241-19-7

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31241-19-7, 5-Methoxy-2,3,3-trimethyl-3H-indole is a indole-building-block compound, ?involved in a variety of chemical synthesis. Rlated chemical reaction is continuously updated

General procedure: Following a modified procedure [22], to a mixture of various substituted 2,3,3-trimethylindole (7.0 mmol), 2-formylpyrrole (1.78 g, 14 mmol), piperidine (12 mL,14 mmol) and ice acetic acid (16.5 mL, 21 mmol) in toluene (50 mL) were addedunder a Dean-Stark trap condition and the mixture was refluxed for 3 h. Thecompletion of the reaction was confirmed by TLC. The brown dark reaction mixturewas cooled, concentrated and separated by column chromatography. The correspondingproducts NDABs as a solid were obtained., 31241-19-7

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Reference:
Article; Li, Yujiao; Yan, Jiaying; Cheng, Kai; Kong, Shuai; Zheng, Kaibo; Wang, Long; Zhang, Nuonuo; Research on Chemical Intermediates; vol. 43; 10; (2017); p. 5337 – 5344;,
Indole alkaloid derivatives as building blocks of natural products from?Bacillus thuringiensis?and?Bacillus velezensis?and their antibacterial and antifungal activity study
Preparation of Indole Containing Building Blocks for the Regiospecific Construction of Indole Appended Pyrazoles and Pyrroles