434958-85-7, N-Boc-5-Hydroxyindole is a indole-building-block compound, ?involved in a variety of chemical synthesis. Rlated chemical reaction is continuously updated
100 mg (0.4 mmol) of 5-hydroxy-1-tert-butyl ester-1H-indole (a) was dissolved in 1 ml of DMF, and 0.5 ml (4 mmol) of p-fluoroacetophenone and 0.96 g (0.8 mmol) were added.Potassium tert-butoxide, stirred at 100 C for 7 hours, diluted with water, extracted with EA,Wash with saturated sodium chloride, dry over anhydrous sodium sulfate, concentrate under reduced pressure, and thenPE: EA=150:1 to get an oil,The yield was 46%.
434958-85-7, The synthetic route of 434958-85-7 has been constantly updated, and we look forward to future research findings.
Reference：
Patent; Tianjin University of Science and Technology; Yu Peng; Guo Na; Lv Hongbin; Fu Ying; Teng Yuou; Wang Dong; (32 pag.)CN110229091; (2019); A;,
Indole alkaloid derivatives as building blocks of natural products from?Bacillus thuringiensis?and?Bacillus velezensis?and their antibacterial and antifungal activity study
Preparation of Indole Containing Building Blocks for the Regiospecific Construction of Indole Appended Pyrazoles and Pyrroles