487-89-8,With the rapid development and complex challenges of chemical substances, new drug synthesis pathways are usually the most effective.487-89-8,Indole-3-carboxaldehyde,as a common compound, the synthetic route is as follows.
General procedure: To a dry dichloromethane solution (10 mL) of the appropriate 1H-indole-3-carbaldehydes(2 mmol), anhydrous potassium carbonate (6 mmol) and benzenesulfonyl chlorides (4 mmol) indry dichloromethane (20 mL) were added, and the mixture was stirred for 12 h at 40 C. After thecompletion of the reaction, excess solvent was removed under reduced pressure to obtain a yellowcrude solid of 3a-3b which was directly used in the next step without purification.
487-89-8 Indole-3-carboxaldehyde 10256, aindole-building-block compound, is more and more widely used in various fields.
Reference£º
Article; Song, Ming-Xia; Li, Song-Hui; Peng, Jiao-Yang; Guo, Ting-Ting; Xu, Wen-Hui; Xiong, Shao-Feng; Deng, Xian-Qing; Molecules; vol. 22; 6; (2017);,
Indole alkaloid derivatives as building blocks of natural products from?Bacillus thuringiensis?and?Bacillus velezensis?and their antibacterial and antifungal activity study
Preparation of Indole Containing Building Blocks for the Regiospecific Construction of Indole Appended Pyrazoles and Pyrroles