5318-27-4, 6-Aminoindole is a indole-building-block compound, ?involved in a variety of chemical synthesis. Rlated chemical reaction is continuously updated
General procedure: A flask was charged with 6-amino Indole (1eq.) in the presenceof dichloromethane (DCM, 0.5 M) and E3N (1.2 eq.) under nitrogenat 0 C. This was followed by addition of substituted benzoylchlorides (1 eq.) to stir at room temperature overnight. The reactionmixture was quenched by water to be extracted with ethyl acetateand dried over anhydrous Na2SO4. The ethyl acetate layer wasevaporated in vacuo. The crude product was purified using silica gelcolumn chromatography using ethyl acetate/hexane solventmixture (50:50) to obtain substituted N-(1H-indole-6-yl) benzamidederivatives
5318-27-4, As the paragraph descriping shows that 5318-27-4 is playing an increasingly important role.
Reference£º
Article; Hendy, Moataz S.; Ali, Aya A.; Ahmed, Lubna; Hossam, Reham; Mostafa, Alaa; Elmazar, Mohamed M.; Naguib, Bassem H.; Attia, Yasmeen M.; Ahmed, Mahmoud Salama; European Journal of Medicinal Chemistry; vol. 166; (2019); p. 281 – 290;,
Indole alkaloid derivatives as building blocks of natural products from?Bacillus thuringiensis?and?Bacillus velezensis?and their antibacterial and antifungal activity study
Preparation of Indole Containing Building Blocks for the Regiospecific Construction of Indole Appended Pyrazoles and Pyrroles