5416-80-8, 2-Methyl-1H-indole-3-carbaldehyde is a indole-building-block compound, ?involved in a variety of chemical synthesis. Rlated chemical reaction is continuously updated
To a solution of 2-Methyl-indole-3-carbaldehyde (1) (2.1?g, 10.0mmoles) in Benzene (50?mL) containing 50% NaOH solution (25?mL), tetrabutylammonium hydrogensulfate (100?mg) and P-Toluenesulfonyl chloride (1.31?g, 10.0mmoles) were added. The mixture was stirred well for 4?h. hen it was poured over crushed ice and extracted with ethyl acetate (3?*?50?mL). The organic layer was separated, washed with water (3?*?25?mL) and dried (MgSO4). Crystallization process by slow solvent evaporation technique using ethyl acetate gave the desired product in 87% yield., 5416-80-8
As the paragraph descriping shows that 5416-80-8 is playing an increasingly important role.
Reference£º
Article; Bellamkonda, Yagna Narayana; Vijaya Chamundeeswari; Journal of Molecular Structure; vol. 1181; (2019); p. 613 – 626;,
Indole alkaloid derivatives as building blocks of natural products from?Bacillus thuringiensis?and?Bacillus velezensis?and their antibacterial and antifungal activity study
Preparation of Indole Containing Building Blocks for the Regiospecific Construction of Indole Appended Pyrazoles and Pyrroles