6146-52-7,With the rapid development and complex challenges of chemical substances, new drug synthesis pathways are usually the most effective.6146-52-7,5-Nitroindole,as a common compound, the synthetic route is as follows.
General procedure: To a solution of 1a-1b (4.5 mmol) in 4 mL ethanol was added80% hydrazine hydrate (2 mL) and 10% palladium charcoal (0.08g). The reaction was refluxed for 10 min and filtered by Celite.The filtrate was dried by sodium sulfate, and concentrated in vacuoto afford compounds 2a-2b, which were used without furtherpurification.
The synthetic route of 6146-52-7 has been constantly updated, and we look forward to future research findings.
Reference£º
Article; Wang, Peng-Fei; Zhang, Yong-Jiao; Wang, Dong; Hu, Hui-Min; Wang, Zhong-Chang; Xu, Chen; Qiu, Han-Yue; Zhu, Hai-Liang; Bioorganic and Medicinal Chemistry; vol. 26; 9; (2018); p. 2372 – 2380;,
Indole alkaloid derivatives as building blocks of natural products from?Bacillus thuringiensis?and?Bacillus velezensis?and their antibacterial and antifungal activity study
Preparation of Indole Containing Building Blocks for the Regiospecific Construction of Indole Appended Pyrazoles and Pyrroles