900514-08-1,900514-08-1, 5-Chloro-3-iodo-7-azaindole is a indole-building-block compound, ?involved in a variety of chemical synthesis. Rlated chemical reaction is continuously updated
A mixture solution of 5-chloro-3-iodo-1H-pyrrolo [2 3-b] pyridine (8 g 28.7 mmol) cesium carbonate (18.7 g 57.5 mmol) and 4-toluenesulfonyl chloride (8.19 g 43.1 mmol) in DMF (80 mL) was stirred at room temperature for 4 h. Afterwards the mixture was poured into water and the suspension was filtered. The crude title compound (8.7 g 70yield) was collected as filter cake. MS 433.1 (M+1)+. It was used direclty in the next step without further purification.
The synthetic route of 900514-08-1 has been constantly updated, and we look forward to future research findings.
Reference：
Patent; SAVIRA PHARMACEUTICALS GMBH; EUROPEAN MOLECULAR BIOLOGY LABORATORY; TAN, Xuefei; ZBINDEN, Katrin Groebke; KUHN, Bernd; WANG, Lisha; LIU, Yongfu; WU, Jun; SHEN, Hong; SHI, Tianlai; (174 pag.)WO2017/133664; (2017); A1;,
Indole alkaloid derivatives as building blocks of natural products from?Bacillus thuringiensis?and?Bacillus velezensis?and their antibacterial and antifungal activity study
Preparation of Indole Containing Building Blocks for the Regiospecific Construction of Indole Appended Pyrazoles and Pyrroles