On August 31, 2005, Sundgren, Andreas; Lahmann, Martina; Oscarson, Stefan published an article.Formula: C16H19NO6S The title of the article was Block synthesis of Streptococcus pneumoniae type 14 capsular polysaccharide structures. And the article contained the following:
Synthesis of a thioglycoside tetrasaccharide block, β-D-Galp-(1â?)-β-DGlcp-(1â?)-[β-D-Galp-(1â?)]-β-D-GlcNPhthp-(1âSEt), corresponding to the repeating unit of Streptococcus pneumoniae serotype 14 CPS is described. Coupling of this block with a spacer followed by removal of an isopropylidene acetal yielded an acceptor, which was elongated with the donor block to give a protected dimer of the repeating unit. Iteration of this methodol. yielded the trimer. Deprotection then produced an octa and a dodecasaccharide derivative ready for conjugation to proteins to afford immunoactive glycoconjugates. The experimental process involved the reaction of Ethyl 2-deoxy-2-(1,3-dihydro-1,3-dioxo-2H-isoindol-2-yl)-1-thio-beta-D-glucopyranoside(cas: 130539-43-4).Formula: C16H19NO6S
The Article related to capsular polysaccharide preparation streptococcus pneumoniae, Carbohydrates: Amines and other aspects.Formula: C16H19NO6S
Referemce:
Indole alkaloid derivatives as building blocks of natural products from Bacillus thuringiensis and Bacillus velezensis and their antibacterial and antifungal activity study,
Preparation of Indole Containing Building Blocks for the Regiospecific Construction of Indole Appended Pyrazoles and Pyrroles