Tag: 118.1359

Efficient copper-catalyzed cross-coupling of nitrogen nucleophiles with N,N-dibenzyl-4-iodobenzenesulfonamide and its application in the synthesis of Celecoxib intermediate was written by Yong, Fui-Fong;Azri, Miskal;Darrell Lim, Yong-En;Teo, Yong-Chua. And the article was included in Tetrahedron in 2020.Formula: C7H6N2 This article mentions the following:

A practical and efficient strategy has been developed for the cross-coupling of N,N-dibenzyl-4-iodobenzenesulfonamide with nitrogen nucleophiles using 0.5-20 mol% of CuI under ligand-free conditions. A variety of nitrogen nucleophiles including nitrogen heterocycles, sulfonamides and amides afforded the corresponding products in moderate to good yields (up to 98%) under the optimized conditions. The application of this catalytic system to the synthesis of Celecoxib intermediate was also successfully demonstrated. In the experiment, the researchers used many compounds, for example, 1H-Pyrrolo[2,3-b]pyridine (cas: 271-63-6Formula: C7H6N2).

1H-Pyrrolo[2,3-b]pyridine (cas: 271-63-6) belongs to indole derivatives. Indole produced by Proteus, Pseudomonas, Escherichia and other species was shown to be a growth promoting factor in Arabidopsis thaliana. In addition to indole, the strain-release chemistry worked for numerous substrates including amines, alcohols, thiols, carboxylic acids, imidazoles, and pyrazoles.Formula: C7H6N2

Referemce:
Indole alkaloid derivatives as building blocks of natural products from聽Bacillus thuringiensis聽and聽Bacillus velezensis聽and their antibacterial and antifungal activity study,
Preparation of Indole Containing Building Blocks for the Regiospecific Construction of Indole Appended Pyrazoles and Pyrroles

Sequentially Catalyzed Three-Component Masuda-Suzuki-Sonogashira Synthesis of Fluorescent 2-Alkynyl-4-(7-azaindol-3-yl)pyrimidines: Three Palladium-Catalyzed Processes in a One-Pot Fashion was written by Driessen, Daniel;Biesen, Lukas;Mueller, Thomas J. J.. And the article was included in Synlett in 2021.Name: 1H-Pyrrolo[2,3-b]pyridine This article mentions the following:

The Masuda-Suzuki-Sonogashira sequence efficiently united in a one-pot fashion, a borylation, an arylation and an alkynylation in the sense of a sequentially Pd-catalyzed three-component reaction to give fluorescent 2-alkynyl-4-(7-azaindol-3-yl)pyrimidines in yields of 24-83%. Time-dependent d.-functional theory calculations supported the electronic structure of the longest wavelength absorption bands, and revealed that this novel consecutive three-component synthesis opened an efficient access to alkynyl meriolins, a novel class of potential inducers of apoptosis. In the experiment, the researchers used many compounds, for example, 1H-Pyrrolo[2,3-b]pyridine (cas: 271-63-6Name: 1H-Pyrrolo[2,3-b]pyridine).

1H-Pyrrolo[2,3-b]pyridine (cas: 271-63-6) belongs to indole derivatives. Indole, also called Benzopyrrole, a heterocyclic organic compound occurring in some flower oils, such as jasmine and orange blossom, in coal tar, and in fecal matter. Moreover, it is known that it controls biofilm formation. However, the role of indole in the cell has not been fully elucidated.Name: 1H-Pyrrolo[2,3-b]pyridine

Referemce:
Indole alkaloid derivatives as building blocks of natural products from聽Bacillus thuringiensis聽and聽Bacillus velezensis聽and their antibacterial and antifungal activity study,
Preparation of Indole Containing Building Blocks for the Regiospecific Construction of Indole Appended Pyrazoles and Pyrroles

Stereoselective Synthesis of Vinylcyclopropa[b]indolines via a Rh-Migration Strategy was written by Guo, Pan;Sun, Wangbin;Liu, Yu;Li, Yong-Xin;Loh, Teck-Peng;Jiang, Yaojia. And the article was included in Organic Letters in 2020.Computed Properties of C7H6N2 This article mentions the following:

A mild rhodium catalytic system has been developed to synthesize vinylcyclopropa[b]indolines through cyclopropanation of indoles with vinyl carbenoids generated from ring opening of cyclopropenes in situ. By employing a Rh-migration strategy, the products can be obtained with good to excellent E:Z ratios (鈮?9:1) and complete diastereoselectivity (鈮?9:1). This method is easy, has a low catalyst loading, and works for a broad range of functionalities. In the experiment, the researchers used many compounds, for example, 1H-Pyrrolo[2,3-b]pyridine (cas: 271-63-6Computed Properties of C7H6N2).

1H-Pyrrolo[2,3-b]pyridine (cas: 271-63-6) belongs to indole derivatives. Indole is an important structural motif of various drugs, therapeutic leads besides its prevalence in numerous natural products, agrochemicals, perfumery, and dyes. Moreover, it is known that it controls biofilm formation. However, the role of indole in the cell has not been fully elucidated.Computed Properties of C7H6N2

Referemce:
Indole alkaloid derivatives as building blocks of natural products from聽Bacillus thuringiensis聽and聽Bacillus velezensis聽and their antibacterial and antifungal activity study,
Preparation of Indole Containing Building Blocks for the Regiospecific Construction of Indole Appended Pyrazoles and Pyrroles

Efficient copper-catalyzed cross-coupling of nitrogen nucleophiles with N,N-dibenzyl-4-iodobenzenesulfonamide and its application in the synthesis of Celecoxib intermediate was written by Yong, Fui-Fong;Azri, Miskal;Darrell Lim, Yong-En;Teo, Yong-Chua. And the article was included in Tetrahedron in 2020.Formula: C7H6N2 This article mentions the following:

A practical and efficient strategy has been developed for the cross-coupling of N,N-dibenzyl-4-iodobenzenesulfonamide with nitrogen nucleophiles using 0.5-20 mol% of CuI under ligand-free conditions. A variety of nitrogen nucleophiles including nitrogen heterocycles, sulfonamides and amides afforded the corresponding products in moderate to good yields (up to 98%) under the optimized conditions. The application of this catalytic system to the synthesis of Celecoxib intermediate was also successfully demonstrated. In the experiment, the researchers used many compounds, for example, 1H-Pyrrolo[2,3-b]pyridine (cas: 271-63-6Formula: C7H6N2).

1H-Pyrrolo[2,3-b]pyridine (cas: 271-63-6) belongs to indole derivatives. Indole produced by Proteus, Pseudomonas, Escherichia and other species was shown to be a growth promoting factor in Arabidopsis thaliana. In addition to indole, the strain-release chemistry worked for numerous substrates including amines, alcohols, thiols, carboxylic acids, imidazoles, and pyrazoles.Formula: C7H6N2

Referemce:
Indole alkaloid derivatives as building blocks of natural products from Bacillus thuringiensis and Bacillus velezensis and their antibacterial and antifungal activity study,
Preparation of Indole Containing Building Blocks for the Regiospecific Construction of Indole Appended Pyrazoles and Pyrroles

Sequentially Catalyzed Three-Component Masuda-Suzuki-Sonogashira Synthesis of Fluorescent 2-Alkynyl-4-(7-azaindol-3-yl)pyrimidines: Three Palladium-Catalyzed Processes in a One-Pot Fashion was written by Driessen, Daniel;Biesen, Lukas;Mueller, Thomas J. J.. And the article was included in Synlett in 2021.Name: 1H-Pyrrolo[2,3-b]pyridine This article mentions the following:

The Masuda-Suzuki-Sonogashira sequence efficiently united in a one-pot fashion, a borylation, an arylation and an alkynylation in the sense of a sequentially Pd-catalyzed three-component reaction to give fluorescent 2-alkynyl-4-(7-azaindol-3-yl)pyrimidines in yields of 24-83%. Time-dependent d.-functional theory calculations supported the electronic structure of the longest wavelength absorption bands, and revealed that this novel consecutive three-component synthesis opened an efficient access to alkynyl meriolins, a novel class of potential inducers of apoptosis. In the experiment, the researchers used many compounds, for example, 1H-Pyrrolo[2,3-b]pyridine (cas: 271-63-6Name: 1H-Pyrrolo[2,3-b]pyridine).

1H-Pyrrolo[2,3-b]pyridine (cas: 271-63-6) belongs to indole derivatives. Indole, also called Benzopyrrole, a heterocyclic organic compound occurring in some flower oils, such as jasmine and orange blossom, in coal tar, and in fecal matter. Moreover, it is known that it controls biofilm formation. However, the role of indole in the cell has not been fully elucidated.Name: 1H-Pyrrolo[2,3-b]pyridine

Referemce:
Indole alkaloid derivatives as building blocks of natural products from Bacillus thuringiensis and Bacillus velezensis and their antibacterial and antifungal activity study,
Preparation of Indole Containing Building Blocks for the Regiospecific Construction of Indole Appended Pyrazoles and Pyrroles

Stereoselective Synthesis of Vinylcyclopropa[b]indolines via a Rh-Migration Strategy was written by Guo, Pan;Sun, Wangbin;Liu, Yu;Li, Yong-Xin;Loh, Teck-Peng;Jiang, Yaojia. And the article was included in Organic Letters in 2020.Computed Properties of C7H6N2 This article mentions the following:

A mild rhodium catalytic system has been developed to synthesize vinylcyclopropa[b]indolines through cyclopropanation of indoles with vinyl carbenoids generated from ring opening of cyclopropenes in situ. By employing a Rh-migration strategy, the products can be obtained with good to excellent E:Z ratios (≤99:1) and complete diastereoselectivity (≤99:1). This method is easy, has a low catalyst loading, and works for a broad range of functionalities. In the experiment, the researchers used many compounds, for example, 1H-Pyrrolo[2,3-b]pyridine (cas: 271-63-6Computed Properties of C7H6N2).

1H-Pyrrolo[2,3-b]pyridine (cas: 271-63-6) belongs to indole derivatives. Indole is an important structural motif of various drugs, therapeutic leads besides its prevalence in numerous natural products, agrochemicals, perfumery, and dyes. Moreover, it is known that it controls biofilm formation. However, the role of indole in the cell has not been fully elucidated.Computed Properties of C7H6N2

Referemce:
Indole alkaloid derivatives as building blocks of natural products from Bacillus thuringiensis and Bacillus velezensis and their antibacterial and antifungal activity study,
Preparation of Indole Containing Building Blocks for the Regiospecific Construction of Indole Appended Pyrazoles and Pyrroles

Stereoselective Synthesis of Vinylcyclopropa[b]indolines via a Rh-Migration Strategy was written by Guo, Pan;Sun, Wangbin;Liu, Yu;Li, Yong-Xin;Loh, Teck-Peng;Jiang, Yaojia. And the article was included in Organic Letters in 2020.Computed Properties of C7H6N2 This article mentions the following:

A mild rhodium catalytic system has been developed to synthesize vinylcyclopropa[b]indolines through cyclopropanation of indoles with vinyl carbenoids generated from ring opening of cyclopropenes in situ. By employing a Rh-migration strategy, the products can be obtained with good to excellent E:Z ratios (≤99:1) and complete diastereoselectivity (≤99:1). This method is easy, has a low catalyst loading, and works for a broad range of functionalities. In the experiment, the researchers used many compounds, for example, 1H-Pyrrolo[2,3-b]pyridine (cas: 271-63-6Computed Properties of C7H6N2).

1H-Pyrrolo[2,3-b]pyridine (cas: 271-63-6) belongs to indole derivatives. Indole is an important structural motif of various drugs, therapeutic leads besides its prevalence in numerous natural products, agrochemicals, perfumery, and dyes. Moreover, it is known that it controls biofilm formation. However, the role of indole in the cell has not been fully elucidated.Computed Properties of C7H6N2

Referemce:
Indole alkaloid derivatives as building blocks of natural products from Bacillus thuringiensis and Bacillus velezensis and their antibacterial and antifungal activity study,
Preparation of Indole Containing Building Blocks for the Regiospecific Construction of Indole Appended Pyrazoles and Pyrroles

Sequentially Catalyzed Three-Component Masuda-Suzuki-Sonogashira Synthesis of Fluorescent 2-Alkynyl-4-(7-azaindol-3-yl)pyrimidines: Three Palladium-Catalyzed Processes in a One-Pot Fashion was written by Driessen, Daniel;Biesen, Lukas;Mueller, Thomas J. J.. And the article was included in Synlett in 2021.Name: 1H-Pyrrolo[2,3-b]pyridine This article mentions the following:

The Masuda-Suzuki-Sonogashira sequence efficiently united in a one-pot fashion, a borylation, an arylation and an alkynylation in the sense of a sequentially Pd-catalyzed three-component reaction to give fluorescent 2-alkynyl-4-(7-azaindol-3-yl)pyrimidines in yields of 24-83%. Time-dependent d.-functional theory calculations supported the electronic structure of the longest wavelength absorption bands, and revealed that this novel consecutive three-component synthesis opened an efficient access to alkynyl meriolins, a novel class of potential inducers of apoptosis. In the experiment, the researchers used many compounds, for example, 1H-Pyrrolo[2,3-b]pyridine (cas: 271-63-6Name: 1H-Pyrrolo[2,3-b]pyridine).

1H-Pyrrolo[2,3-b]pyridine (cas: 271-63-6) belongs to indole derivatives. Indole, also called Benzopyrrole, a heterocyclic organic compound occurring in some flower oils, such as jasmine and orange blossom, in coal tar, and in fecal matter. Moreover, it is known that it controls biofilm formation. However, the role of indole in the cell has not been fully elucidated.Name: 1H-Pyrrolo[2,3-b]pyridine

Referemce:
Indole alkaloid derivatives as building blocks of natural products from Bacillus thuringiensis and Bacillus velezensis and their antibacterial and antifungal activity study,
Preparation of Indole Containing Building Blocks for the Regiospecific Construction of Indole Appended Pyrazoles and Pyrroles

Stereoselective Synthesis of Vinylcyclopropa[b]indolines via a Rh-Migration Strategy was written by Guo, Pan;Sun, Wangbin;Liu, Yu;Li, Yong-Xin;Loh, Teck-Peng;Jiang, Yaojia. And the article was included in Organic Letters in 2020.Computed Properties of C7H6N2 This article mentions the following:

A mild rhodium catalytic system has been developed to synthesize vinylcyclopropa[b]indolines through cyclopropanation of indoles with vinyl carbenoids generated from ring opening of cyclopropenes in situ. By employing a Rh-migration strategy, the products can be obtained with good to excellent E:Z ratios (≤99:1) and complete diastereoselectivity (≤99:1). This method is easy, has a low catalyst loading, and works for a broad range of functionalities. In the experiment, the researchers used many compounds, for example, 1H-Pyrrolo[2,3-b]pyridine (cas: 271-63-6Computed Properties of C7H6N2).

1H-Pyrrolo[2,3-b]pyridine (cas: 271-63-6) belongs to indole derivatives. Indole is an important structural motif of various drugs, therapeutic leads besides its prevalence in numerous natural products, agrochemicals, perfumery, and dyes. Moreover, it is known that it controls biofilm formation. However, the role of indole in the cell has not been fully elucidated.Computed Properties of C7H6N2

Referemce:
Indole alkaloid derivatives as building blocks of natural products from Bacillus thuringiensis and Bacillus velezensis and their antibacterial and antifungal activity study,
Preparation of Indole Containing Building Blocks for the Regiospecific Construction of Indole Appended Pyrazoles and Pyrroles