1224724-39-3, Methyl 4-bromo-1H-indole-7-carboxylate is a indole-building-block compound, ?involved in a variety of chemical synthesis. Rlated chemical reaction is continuously updated
To a mixed solution of compound 267c (800 mg, 3.149 mmol) in methanol (6 mL) and tetrahydrofuran (6 mL) was added a solution of lithium hydroxide in water (12 mL) at room temperature. The mixture was stirred at room temperature for 2.5 hours. The reaction solution was concentrated under reduced pressure, water was added to the residue and neutralized with dilute hydrochloric acid, and then extracted with ethyl acetate (80 mL ¡Á 3).The organic phases were combined, washed with saturated brine, and dried over anhydrous sodium sulfate. The filtrate was concentrated under reduced pressure, ethyl acetate and petroleum ether were added to the residue, and the white solid compound 267d, 4-bromo-1H-indole-7-carboxylic acid (360 mg, 44.8% yield) was collected by filtration.
1224724-39-3, As the paragraph descriping shows that 1224724-39-3 is playing an increasingly important role.
Reference£º
Patent; Jiaxing Tekeluo Biological Technology Co., Ltd.; Xing Li; Li Guanqun; Wang Xiaolei; Cai Yuting; Jiang Xiang; Pan Xiang; Zhu Wenhao; Wang Yang; Wang Zengquan; (83 pag.)CN110627775; (2019); A;,
Indole alkaloid derivatives as building blocks of natural products from?Bacillus thuringiensis?and?Bacillus velezensis?and their antibacterial and antifungal activity study
Preparation of Indole Containing Building Blocks for the Regiospecific Construction of Indole Appended Pyrazoles and Pyrroles