Tag: 173.2542

Synthesis and photochromic properties of novel spiro[indoline-quinoline]oxazine derivatives was written by Zhou, Yan;Pang, Meili;Li, Jingjing;Li, Hong. And the article was included in Dyes and Pigments in 2014.Recommanded Product: 118-12-7 This article mentions the following:

A series of novel spirooxazine derivatives containing nitrogen heterocycles have been synthesized and characterized by ¹H NMR, ¹³C NMR, IR and HRMS in this paper, and the photochromic behaviors of the compounds have been studied in different solutions and the compounds were embedded into a poly(methylmethacrylate) and poly(vinyl butyral) matrix (PMMA, PVB). In solutions, they showed thermochromism and acidichromism. Embedded into polymeric films, the photochromic kinetics of the thermal decoloration of the compounds significantly changed and it was found that the decoloration curves fitted biexponential function. Detailed studies showed that representative compound 1 [1,3,3-trimethyl-6′-piperidino-spiro(indoline-2,3′-[3H]-quinolino[2,1-b][1,4]oxazine)] exhibited high fatigue resistance in poly(methylmethacrylate) and poly(vinyl butyral) matrix. In the experiment, the researchers used many compounds, for example, 1,3,3-Trimethyl-2-methyleneindoline (cas: 118-12-7Recommanded Product: 118-12-7).

1,3,3-Trimethyl-2-methyleneindoline (cas: 118-12-7) belongs to indole derivatives. Indole produced by Proteus, Pseudomonas, Escherichia and other species was shown to be a growth promoting factor in Arabidopsis thaliana. In addition to indole, the strain-release chemistry worked for numerous substrates including amines, alcohols, thiols, carboxylic acids, imidazoles, and pyrazoles.Recommanded Product: 118-12-7

Referemce:
Indole alkaloid derivatives as building blocks of natural products from聽Bacillus thuringiensis聽and聽Bacillus velezensis聽and their antibacterial and antifungal activity study,
Preparation of Indole Containing Building Blocks for the Regiospecific Construction of Indole Appended Pyrazoles and Pyrroles

Control of Imine Exchange Kinetics with Photoswitches to Modulate Self-Healing in Polysiloxane Networks by Light Illumination was written by Kathan, Michael;Kovaricek, Petr;Jurissek, Christoph;Senf, Antti;Dallmann, Andre;Thuenemann, Andreas F.;Hecht, Stefan. And the article was included in Angewandte Chemie, International Edition in 2016.COA of Formula: C12H15N This article mentions the following:

Various aldehyde-containing photoswitches have been developed whose reactivity toward amines can be controlled externally. A thermally stable bifunctional diarylethene, which in its ring-closed form exhibits imine formation accelerated by one order of magnitude, was used as a photoswitchable crosslinker and mixed with a com. available amino-functionalized polysiloxane to yield a rubbery material with viscoelastic and self-healing properties that can be reversibly tuned by irradiation In the experiment, the researchers used many compounds, for example, 1,3,3-Trimethyl-2-methyleneindoline (cas: 118-12-7COA of Formula: C12H15N).

1,3,3-Trimethyl-2-methyleneindoline (cas: 118-12-7) belongs to indole derivatives. Indole exists overwhelmingly in the 1H-indole form as do other simple indoles. They are capable of binding to a variety of receptors with high affinity and thus have applications in a wide range of therapeutic areas.COA of Formula: C12H15N

Referemce:
Indole alkaloid derivatives as building blocks of natural products from聽Bacillus thuringiensis聽and聽Bacillus velezensis聽and their antibacterial and antifungal activity study,
Preparation of Indole Containing Building Blocks for the Regiospecific Construction of Indole Appended Pyrazoles and Pyrroles

Nonlinear optical properties of chromophores with indolizine donors: Theoretical study was written by Levitskaya, Alina I.;Kalinin, Alexey A.;Fominykh, Olga D.;Vasilyev, Ilya V.;Balakina, Marina Yu.. And the article was included in Computational & Theoretical Chemistry in 2016.Category: indole-building-block This article mentions the following:

New class of nonlinear optical chromophores with donors containing indolizine moiety is proposed. Dipole moment and first hyperpolarizability values of the chromophores, which are analogs of FTC, CLD and OLD chromophores, containing 1-methyl-2-phenylindolizin-3-yl (MPI-3) or 3-methyl-2-phenylindolizin-1-yl (MPI-1) donors (instead of diethylaminophenyl), 3-cyano-2-dicyanomethylene-5,5-dimethyl-1,5-dihydrofuran-4-yl (TCF) acceptor, and 2,5-divinylthiophene, octatetraene and 2,2′-divinylbithiophene 蟺-electron bridge, are calculated by DFT technique. Chromophores with named donors and acceptors and 3,7-divinylquinoxalin-2-one 蟺-electron bridge are also studied. In most cases higher values of first hyperpolarizability were obtained for chromophores with MPI-3 donor, this being in accordance with the electron d. distribution in these fragments. The change of dimethylaniline donor fragment for indolizine one results in the growth of the first hyperpolarizability values. This observation holds also for chromophores with divinylquinoxalinone 蟺-electron bridge, in which higher values of first hyperpolarizability are obtained when the donor moiety is connected through vinylene group at position 3 rather than at position 7 of the quinoxalinone system. In the experiment, the researchers used many compounds, for example, 1,3,3-Trimethyl-2-methyleneindoline (cas: 118-12-7Category: indole-building-block).

1,3,3-Trimethyl-2-methyleneindoline (cas: 118-12-7) belongs to indole derivatives. Indole exists overwhelmingly in the 1H-indole form as do other simple indoles. In addition to indole, the strain-release chemistry worked for numerous substrates including amines, alcohols, thiols, carboxylic acids, imidazoles, and pyrazoles.Category: indole-building-block

Referemce:
Indole alkaloid derivatives as building blocks of natural products from聽Bacillus thuringiensis聽and聽Bacillus velezensis聽and their antibacterial and antifungal activity study,
Preparation of Indole Containing Building Blocks for the Regiospecific Construction of Indole Appended Pyrazoles and Pyrroles

Spiropyran-azobenzene-DBU system as solvent indicator was written by Xu, Zhiping;Li, Shen;Shen, Yujun;Chen, Meijun;Shao, Xusheng. And the article was included in Tetrahedron Letters in 2018.Formula: C12H15N This article mentions the following:

A dyad bearing azobenzene and spiropyran units was synthesized and its applications in indicating the polarity and protic or aprotic properties of a solvent were explored. The spiropyran-azobenzene derivative (SPAB) can be induced to different forms in different miscellaneous solvents accompanied with different color changes and spectral characteristics at the presence of organic base DBU. In a nonpolar or low-polar solvent, SPAB exists in thermostable spiropyran form with yellow color output. While in an aprotic polar solvent, the spiropyran part isomerized to merocyanine form giving a blue color. When SPAB is subjected to a protic solvent, the alkylation reaction occurs at the oxygen generating the alkylated-SPAB with red color. This solvent-dependent property can be used for discriminating solvent type. In the experiment, the researchers used many compounds, for example, 1,3,3-Trimethyl-2-methyleneindoline (cas: 118-12-7Formula: C12H15N).

1,3,3-Trimethyl-2-methyleneindoline (cas: 118-12-7) belongs to indole derivatives. Indole exists overwhelmingly in the 1H-indole form as do other simple indoles. Moreover, it is known that it controls biofilm formation. However, the role of indole in the cell has not been fully elucidated.Formula: C12H15N

Referemce:
Indole alkaloid derivatives as building blocks of natural products from聽Bacillus thuringiensis聽and聽Bacillus velezensis聽and their antibacterial and antifungal activity study,
Preparation of Indole Containing Building Blocks for the Regiospecific Construction of Indole Appended Pyrazoles and Pyrroles

Spiropyran in situ switching: A real-time fluorescence strategy for tracking DNA G-quadruplexes in live cells was written by Li, Jin;Yin, Xinchi;Li, Bin;Li, Xiaokang;Pan, Yuanjiang;Li, Jian;Guo, Yuan. And the article was included in Analytical Chemistry (Washington, DC, United States) in 2019.SDS of cas: 118-12-7 This article mentions the following:

DNA G-quadruplexes (G4s) in vivo have been linked to cancer and other diseases such as neurol. disorders. Nondestructive fast detection of endogenous DNA G4s can provide specific real-time information, which is of particular interest for clinic accurate diagnosis. However, tools to probe live-cell endogenous DNA G4s in real time are very limited. Herein, we report the design and development of a fluorescent mol. QIN for the real-time detection of endogenous DNA G4s in live cells with the aid of a new spiropyran in situ switching (SIS) strategy. The lipophilic spiropyran-linked QIN differs from the other probes in that it can enter live cells readily within 15 s and can be in situ induced by DNA G4s to adopt its charged open form, causing a large red shift in the fluorescent emission wavelength. Live-cell super-resolution fluorescent imaging suggests that the SIS-based probe has high photostability and can be applied for the accurate detection of DNA G4s in complex biosystems with very high sensitivity and selectivity. In the experiment, the researchers used many compounds, for example, 1,3,3-Trimethyl-2-methyleneindoline (cas: 118-12-7SDS of cas: 118-12-7).

1,3,3-Trimethyl-2-methyleneindoline (cas: 118-12-7) belongs to indole derivatives. In addition to tryptophan, indigo, and indoleacetic acid, numerous compounds obtainable from plant or animal sources contain the indole molecular structure.Indole was synthesized in moderate yield via an o-naphthoquinone catalyzed tandem cross-coupling of substituted aniline and benzylamine under aerobic oxidation conditions.SDS of cas: 118-12-7

Referemce:
Indole alkaloid derivatives as building blocks of natural products from聽Bacillus thuringiensis聽and聽Bacillus velezensis聽and their antibacterial and antifungal activity study,
Preparation of Indole Containing Building Blocks for the Regiospecific Construction of Indole Appended Pyrazoles and Pyrroles

Palladium Nanoparticles in Glycerol: A Versatile Catalytic System for C-X Bond Formation and Hydrogenation Processes was written by Chahdoura, Faouzi;Pradel, Christian;Gomez, Montserrat. And the article was included in Advanced Synthesis & Catalysis in 2013.Related Products of 118-12-7 This article mentions the following:

Palladium nanoparticles stabilized by tris(3-sulfophenyl)phosphine trisodium salt in neat glycerol have been synthesized starting from both Pd(II) and Pd(0) species and fully characterized. The versatility of this innovative catalytic colloidal solution has been proved by its efficient application in C-X bond formation processes (X = C, N, P, S) and C-C multiple bond hydrogenation reactions. The catalytic glycerol phase could be recycled more than ten times, preserving its activity and selectivity. The scope of each of these processes has demonstrated the power of the as-prepared catalyst, isolating the corresponding expected products in yields higher than 90%. The dual catalytic behavior of this glycerol phase, associated to the metallic nanocatalysts used in wet medium (mol.- and surface-like behavior), has allowed attractive applications in one-pot multi-step transformations catalyzed by palladium, such as C-C coupling followed by hydrogenation, without isolation of intermediates using only one catalytic precursor. In the experiment, the researchers used many compounds, for example, 1,3,3-Trimethyl-2-methyleneindoline (cas: 118-12-7Related Products of 118-12-7).

1,3,3-Trimethyl-2-methyleneindoline (cas: 118-12-7) belongs to indole derivatives. Indole produced by Proteus, Pseudomonas, Escherichia and other species was shown to be a growth promoting factor in Arabidopsis thaliana. In addition to indole, the strain-release chemistry worked for numerous substrates including amines, alcohols, thiols, carboxylic acids, imidazoles, and pyrazoles.Related Products of 118-12-7

Referemce:
Indole alkaloid derivatives as building blocks of natural products from聽Bacillus thuringiensis聽and聽Bacillus velezensis聽and their antibacterial and antifungal activity study,
Preparation of Indole Containing Building Blocks for the Regiospecific Construction of Indole Appended Pyrazoles and Pyrroles

Multicomponent Tandem Polymerization of Aromatic Alkynes, Carbonyl Chloride, and Fischer’s Base toward Poly(diene merocyanine)s was written by Tang, Xiaojuan;Zhang, Lihui;Hu, Rongrong;Tang, Ben Zhong. And the article was included in Chinese Journal of Chemistry in 2019.Safety of 1,3,3-Trimethyl-2-methyleneindoline This article mentions the following:

Summary of main observation and conclusion : Multicomponent polymerization (MCP) is a popular tool to construct polymers with diverse structure, simple operation, and high efficiency, which faces the challenges of limited product structures. Multicomponent tandem polymerization (MCTP), combining two or multiple reactions in a one-pot fashion, could expand the scope of MCP and enrich the polymer structures. Herein, a one-pot three-component tandem polymerization of diynes, carbonyl chloride, and Fischer’s base has been developed to afford conjugated poly(diene merocyanine)s with mild condition, satisfactory mol. weights (M_w up to 10900 g/mol) and yields (up to 81%). The polymers enjoy good solubility and high thermal stability. The unique emission behavior of the model compound and polymer show that they are aggregation-induced emission (AIE)-active, suggesting that the diene merocyanine moiety is a potential AIEgen. This MCTP shows great potential in the preparation of functional polymer materials, which could build new AIE functional units directly from the polymerization, demonstrating its synthetic simplicity and elegance. In the experiment, the researchers used many compounds, for example, 1,3,3-Trimethyl-2-methyleneindoline (cas: 118-12-7Safety of 1,3,3-Trimethyl-2-methyleneindoline).

1,3,3-Trimethyl-2-methyleneindoline (cas: 118-12-7) belongs to indole derivatives. Indole exists overwhelmingly in the 1H-indole form as do other simple indoles. They are capable of binding to a variety of receptors with high affinity and thus have applications in a wide range of therapeutic areas.Safety of 1,3,3-Trimethyl-2-methyleneindoline

Referemce:
Indole alkaloid derivatives as building blocks of natural products from聽Bacillus thuringiensis聽and聽Bacillus velezensis聽and their antibacterial and antifungal activity study,
Preparation of Indole Containing Building Blocks for the Regiospecific Construction of Indole Appended Pyrazoles and Pyrroles

Synthesis and photochromic properties of novel spiro[indoline-quinoline]oxazine derivatives was written by Zhou, Yan;Pang, Meili;Li, Jingjing;Li, Hong. And the article was included in Dyes and Pigments in 2014.Recommanded Product: 118-12-7 This article mentions the following:

A series of novel spirooxazine derivatives containing nitrogen heterocycles have been synthesized and characterized by ¹H NMR, ¹³C NMR, IR and HRMS in this paper, and the photochromic behaviors of the compounds have been studied in different solutions and the compounds were embedded into a poly(methylmethacrylate) and poly(vinyl butyral) matrix (PMMA, PVB). In solutions, they showed thermochromism and acidichromism. Embedded into polymeric films, the photochromic kinetics of the thermal decoloration of the compounds significantly changed and it was found that the decoloration curves fitted biexponential function. Detailed studies showed that representative compound 1 [1,3,3-trimethyl-6′-piperidino-spiro(indoline-2,3′-[3H]-quinolino[2,1-b][1,4]oxazine)] exhibited high fatigue resistance in poly(methylmethacrylate) and poly(vinyl butyral) matrix. In the experiment, the researchers used many compounds, for example, 1,3,3-Trimethyl-2-methyleneindoline (cas: 118-12-7Recommanded Product: 118-12-7).

1,3,3-Trimethyl-2-methyleneindoline (cas: 118-12-7) belongs to indole derivatives. Indole produced by Proteus, Pseudomonas, Escherichia and other species was shown to be a growth promoting factor in Arabidopsis thaliana. In addition to indole, the strain-release chemistry worked for numerous substrates including amines, alcohols, thiols, carboxylic acids, imidazoles, and pyrazoles.Recommanded Product: 118-12-7

Referemce:
Indole alkaloid derivatives as building blocks of natural products from Bacillus thuringiensis and Bacillus velezensis and their antibacterial and antifungal activity study,
Preparation of Indole Containing Building Blocks for the Regiospecific Construction of Indole Appended Pyrazoles and Pyrroles

Control of Imine Exchange Kinetics with Photoswitches to Modulate Self-Healing in Polysiloxane Networks by Light Illumination was written by Kathan, Michael;Kovaricek, Petr;Jurissek, Christoph;Senf, Antti;Dallmann, Andre;Thuenemann, Andreas F.;Hecht, Stefan. And the article was included in Angewandte Chemie, International Edition in 2016.COA of Formula: C12H15N This article mentions the following:

Various aldehyde-containing photoswitches have been developed whose reactivity toward amines can be controlled externally. A thermally stable bifunctional diarylethene, which in its ring-closed form exhibits imine formation accelerated by one order of magnitude, was used as a photoswitchable crosslinker and mixed with a com. available amino-functionalized polysiloxane to yield a rubbery material with viscoelastic and self-healing properties that can be reversibly tuned by irradiation In the experiment, the researchers used many compounds, for example, 1,3,3-Trimethyl-2-methyleneindoline (cas: 118-12-7COA of Formula: C12H15N).

1,3,3-Trimethyl-2-methyleneindoline (cas: 118-12-7) belongs to indole derivatives. Indole exists overwhelmingly in the 1H-indole form as do other simple indoles. They are capable of binding to a variety of receptors with high affinity and thus have applications in a wide range of therapeutic areas.COA of Formula: C12H15N

Referemce:
Indole alkaloid derivatives as building blocks of natural products from Bacillus thuringiensis and Bacillus velezensis and their antibacterial and antifungal activity study,
Preparation of Indole Containing Building Blocks for the Regiospecific Construction of Indole Appended Pyrazoles and Pyrroles

Nonlinear optical properties of chromophores with indolizine donors: Theoretical study was written by Levitskaya, Alina I.;Kalinin, Alexey A.;Fominykh, Olga D.;Vasilyev, Ilya V.;Balakina, Marina Yu.. And the article was included in Computational & Theoretical Chemistry in 2016.Category: indole-building-block This article mentions the following:

New class of nonlinear optical chromophores with donors containing indolizine moiety is proposed. Dipole moment and first hyperpolarizability values of the chromophores, which are analogs of FTC, CLD and OLD chromophores, containing 1-methyl-2-phenylindolizin-3-yl (MPI-3) or 3-methyl-2-phenylindolizin-1-yl (MPI-1) donors (instead of diethylaminophenyl), 3-cyano-2-dicyanomethylene-5,5-dimethyl-1,5-dihydrofuran-4-yl (TCF) acceptor, and 2,5-divinylthiophene, octatetraene and 2,2′-divinylbithiophene π-electron bridge, are calculated by DFT technique. Chromophores with named donors and acceptors and 3,7-divinylquinoxalin-2-one π-electron bridge are also studied. In most cases higher values of first hyperpolarizability were obtained for chromophores with MPI-3 donor, this being in accordance with the electron d. distribution in these fragments. The change of dimethylaniline donor fragment for indolizine one results in the growth of the first hyperpolarizability values. This observation holds also for chromophores with divinylquinoxalinone π-electron bridge, in which higher values of first hyperpolarizability are obtained when the donor moiety is connected through vinylene group at position 3 rather than at position 7 of the quinoxalinone system. In the experiment, the researchers used many compounds, for example, 1,3,3-Trimethyl-2-methyleneindoline (cas: 118-12-7Category: indole-building-block).

1,3,3-Trimethyl-2-methyleneindoline (cas: 118-12-7) belongs to indole derivatives. Indole exists overwhelmingly in the 1H-indole form as do other simple indoles. In addition to indole, the strain-release chemistry worked for numerous substrates including amines, alcohols, thiols, carboxylic acids, imidazoles, and pyrazoles.Category: indole-building-block

Referemce:
Indole alkaloid derivatives as building blocks of natural products from Bacillus thuringiensis and Bacillus velezensis and their antibacterial and antifungal activity study,
Preparation of Indole Containing Building Blocks for the Regiospecific Construction of Indole Appended Pyrazoles and Pyrroles