Tag: 272.14

Chi, Zhuomin et al. published their research in Chinese Chemical Letters in 2022 | CAS: 83515-06-4

5-Bromo-2-phenyl-1H-indole (cas: 83515-06-4) belongs to indole derivatives. The indole subunit is an almost ubiquitous component of biologically active natural products, and its study has been the focus of research for decades. Indole plays a fundamental role for QS in E. coli, being one of the signal molecules responsible for the transcription of a variety of genes (gabT, and tnaB ASTD). Safety of 5-Bromo-2-phenyl-1H-indole

Dearomative spirocyclization via visible-light-induced reductive hydroarylation of non-activated arenes was written by Chi, Zhuomin;Gao, Yuzhen;Yang, Lei;Zhou, Chunlin;Zhang, Meng;Cheng, Peiming;Li, Gang. And the article was included in Chinese Chemical Letters in 2022.Safety of 5-Bromo-2-phenyl-1H-indole This article mentions the following:

A visible-light-induced spirocyclizative hydroarylation via reductive dearomatization of a series of non-activated arenes including 2-Ph indoles and naphthalene derivatives under mild conditions was described. An intriguing chemoselective dearomative hydroarylation of 2-Ph indoles was presented. This dearomative hydroarylation protocol rapidly delivered valuable spirocycles with carbon-carbon double bonds from readily accessible aromatic precursors in a single step. In the experiment, the researchers used many compounds, for example, 5-Bromo-2-phenyl-1H-indole (cas: 83515-06-4Safety of 5-Bromo-2-phenyl-1H-indole).

5-Bromo-2-phenyl-1H-indole (cas: 83515-06-4) belongs to indole derivatives. The indole subunit is an almost ubiquitous component of biologically active natural products, and its study has been the focus of research for decades. Indole plays a fundamental role for QS in E. coli, being one of the signal molecules responsible for the transcription of a variety of genes (gabT, and tnaB ASTD). Safety of 5-Bromo-2-phenyl-1H-indole

Referemce:
Indole alkaloid derivatives as building blocks of natural products from聽Bacillus thuringiensis聽and聽Bacillus velezensis聽and their antibacterial and antifungal activity study,
Preparation of Indole Containing Building Blocks for the Regiospecific Construction of Indole Appended Pyrazoles and Pyrroles

Shan, Xiang-Huan et al. published their research in Nature Communications in 2019 | CAS: 83515-06-4

5-Bromo-2-phenyl-1H-indole (cas: 83515-06-4) belongs to indole derivatives. Indole, also called Benzopyrrole, a heterocyclic organic compound occurring in some flower oils, such as jasmine and orange blossom, in coal tar, and in fecal matter.Indole was synthesized in moderate yield via an o-naphthoquinone catalyzed tandem cross-coupling of substituted aniline and benzylamine under aerobic oxidation conditions.Reference of 83515-06-4

Copper-catalyzed oxidative benzylic C-H cyclization via iminyl radical from intermolecular anion-radical redox relay was written by Shan, Xiang-Huan;Zheng, Hong-Xing;Yang, Bo;Tie, Lin;Fu, Jia-Le;Qu, Jian-Ping;Kang, Yan-Biao. And the article was included in Nature Communications in 2019.Reference of 83515-06-4 This article mentions the following:

The combination of base-promoted benzylic C-H cleavage and copper-catalyzed carbanion-radical redox relay was reported. Catalytic amount of naturally abundant and inexpensive copper salt, such as copper(II) sulfate, was used for anion-radical redox relay without any external oxidant. By avoiding using N-O/N-N homolysis or radical initiators to generate iminyl radicals, this strategy realized modular synthesis of N-H indoles and analogs from abundant feedstocks, such as toluene and nitrile derivatives, and also enabled rapid synthesis of large scale pharmaceuticals. In the experiment, the researchers used many compounds, for example, 5-Bromo-2-phenyl-1H-indole (cas: 83515-06-4Reference of 83515-06-4).

5-Bromo-2-phenyl-1H-indole (cas: 83515-06-4) belongs to indole derivatives. Indole, also called Benzopyrrole, a heterocyclic organic compound occurring in some flower oils, such as jasmine and orange blossom, in coal tar, and in fecal matter.Indole was synthesized in moderate yield via an o-naphthoquinone catalyzed tandem cross-coupling of substituted aniline and benzylamine under aerobic oxidation conditions.Reference of 83515-06-4

Referemce:
Indole alkaloid derivatives as building blocks of natural products from聽Bacillus thuringiensis聽and聽Bacillus velezensis聽and their antibacterial and antifungal activity study,
Preparation of Indole Containing Building Blocks for the Regiospecific Construction of Indole Appended Pyrazoles and Pyrroles

Hiremath, Shivayogi P. et al. published their research in Indian Journal of Chemistry, Section B: Organic Chemistry Including Medicinal Chemistry in 1982 | CAS: 83515-06-4

5-Bromo-2-phenyl-1H-indole (cas: 83515-06-4) belongs to indole derivatives. Indole is an important structural motif of various drugs, therapeutic leads besides its prevalence in numerous natural products, agrochemicals, perfumery, and dyes. Due to this activity, the indole ring system has become an important component or intermediate in the synthesis of heterocycles.Related Products of 83515-06-4

Synthesis and reactions of 2-phenylindol-3-ones was written by Hiremath, Shivayogi P.;Biradar, Jaiprakash S.;Mruthyunjayaswamy, B. H. M.. And the article was included in Indian Journal of Chemistry, Section B: Organic Chemistry Including Medicinal Chemistry in 1982.Related Products of 83515-06-4 This article mentions the following:

2-Phenyl-3-aminoindoles were synthesized and converted into the corresponding 2-phenylindol-3-ones (I), which on reaction with o-phenylenediamines and nitrostyrene gave 9-substituted 5H-5a,6-dihydro-5a-phenylindolo[2,3-b]quinoxalines and 9-substituted 6,6a,7,12a-tetrahydro-6-nitro-6a-phenylindolo[1,2-a]quinolin-7-ones resp. Semicarbazones and thiosemicarbazones were also prepared from I. The antimicrobial activity of some of the compounds has also been studied. In the experiment, the researchers used many compounds, for example, 5-Bromo-2-phenyl-1H-indole (cas: 83515-06-4Related Products of 83515-06-4).

5-Bromo-2-phenyl-1H-indole (cas: 83515-06-4) belongs to indole derivatives. Indole is an important structural motif of various drugs, therapeutic leads besides its prevalence in numerous natural products, agrochemicals, perfumery, and dyes. Due to this activity, the indole ring system has become an important component or intermediate in the synthesis of heterocycles.Related Products of 83515-06-4

Referemce:
Indole alkaloid derivatives as building blocks of natural products from聽Bacillus thuringiensis聽and聽Bacillus velezensis聽and their antibacterial and antifungal activity study,
Preparation of Indole Containing Building Blocks for the Regiospecific Construction of Indole Appended Pyrazoles and Pyrroles

Shan, Xiang-Huan et al. published their research in Nature Communications in 2019 | CAS: 83515-06-4

5-Bromo-2-phenyl-1H-indole (cas: 83515-06-4) belongs to indole derivatives. Indole, also called Benzopyrrole, a heterocyclic organic compound occurring in some flower oils, such as jasmine and orange blossom, in coal tar, and in fecal matter.Indole was synthesized in moderate yield via an o-naphthoquinone catalyzed tandem cross-coupling of substituted aniline and benzylamine under aerobic oxidation conditions.Reference of 83515-06-4

Copper-catalyzed oxidative benzylic C-H cyclization via iminyl radical from intermolecular anion-radical redox relay was written by Shan, Xiang-Huan;Zheng, Hong-Xing;Yang, Bo;Tie, Lin;Fu, Jia-Le;Qu, Jian-Ping;Kang, Yan-Biao. And the article was included in Nature Communications in 2019.Reference of 83515-06-4 This article mentions the following:

The combination of base-promoted benzylic C-H cleavage and copper-catalyzed carbanion-radical redox relay was reported. Catalytic amount of naturally abundant and inexpensive copper salt, such as copper(II) sulfate, was used for anion-radical redox relay without any external oxidant. By avoiding using N-O/N-N homolysis or radical initiators to generate iminyl radicals, this strategy realized modular synthesis of N-H indoles and analogs from abundant feedstocks, such as toluene and nitrile derivatives, and also enabled rapid synthesis of large scale pharmaceuticals. In the experiment, the researchers used many compounds, for example, 5-Bromo-2-phenyl-1H-indole (cas: 83515-06-4Reference of 83515-06-4).

5-Bromo-2-phenyl-1H-indole (cas: 83515-06-4) belongs to indole derivatives. Indole, also called Benzopyrrole, a heterocyclic organic compound occurring in some flower oils, such as jasmine and orange blossom, in coal tar, and in fecal matter.Indole was synthesized in moderate yield via an o-naphthoquinone catalyzed tandem cross-coupling of substituted aniline and benzylamine under aerobic oxidation conditions.Reference of 83515-06-4

Referemce:
Indole alkaloid derivatives as building blocks of natural products from Bacillus thuringiensis and Bacillus velezensis and their antibacterial and antifungal activity study,
Preparation of Indole Containing Building Blocks for the Regiospecific Construction of Indole Appended Pyrazoles and Pyrroles

Hiremath, Shivayogi P. et al. published their research in Indian Journal of Chemistry, Section B: Organic Chemistry Including Medicinal Chemistry in 1982 | CAS: 83515-06-4

5-Bromo-2-phenyl-1H-indole (cas: 83515-06-4) belongs to indole derivatives. Indole is an important structural motif of various drugs, therapeutic leads besides its prevalence in numerous natural products, agrochemicals, perfumery, and dyes. Due to this activity, the indole ring system has become an important component or intermediate in the synthesis of heterocycles.Related Products of 83515-06-4

Synthesis and reactions of 2-phenylindol-3-ones was written by Hiremath, Shivayogi P.;Biradar, Jaiprakash S.;Mruthyunjayaswamy, B. H. M.. And the article was included in Indian Journal of Chemistry, Section B: Organic Chemistry Including Medicinal Chemistry in 1982.Related Products of 83515-06-4 This article mentions the following:

2-Phenyl-3-aminoindoles were synthesized and converted into the corresponding 2-phenylindol-3-ones (I), which on reaction with o-phenylenediamines and nitrostyrene gave 9-substituted 5H-5a,6-dihydro-5a-phenylindolo[2,3-b]quinoxalines and 9-substituted 6,6a,7,12a-tetrahydro-6-nitro-6a-phenylindolo[1,2-a]quinolin-7-ones resp. Semicarbazones and thiosemicarbazones were also prepared from I. The antimicrobial activity of some of the compounds has also been studied. In the experiment, the researchers used many compounds, for example, 5-Bromo-2-phenyl-1H-indole (cas: 83515-06-4Related Products of 83515-06-4).

5-Bromo-2-phenyl-1H-indole (cas: 83515-06-4) belongs to indole derivatives. Indole is an important structural motif of various drugs, therapeutic leads besides its prevalence in numerous natural products, agrochemicals, perfumery, and dyes. Due to this activity, the indole ring system has become an important component or intermediate in the synthesis of heterocycles.Related Products of 83515-06-4

Referemce:
Indole alkaloid derivatives as building blocks of natural products from Bacillus thuringiensis and Bacillus velezensis and their antibacterial and antifungal activity study,
Preparation of Indole Containing Building Blocks for the Regiospecific Construction of Indole Appended Pyrazoles and Pyrroles