Tag: 400-500

《Synthesis of analogues of calicheamicin and neocarzinostatin chromophore》 was written by Cirla, Alessandra; McHale, Angela R.; Mann, John. Computed Properties of C22H25NO9S And the article was included in Tetrahedron on April 26 ,2004. The article conveys some information:

The work presents a synthetic route to the CD ring of calicheamicin and in the case of neocarzinostatin an approach to a functionalized cyclopentane-1,3-diol containing the naturally occurring naphthoate and a glucosamine motif. In the case of the NCS derivative some biol. activity (cytotoxicity) was observed The experimental process involved the reaction of Ethyl 3,4,6-tri-O-acetyl-2-deoxy-2-phthalimido-β-D-thioglucopyranoside(cas: 99409-32-2Computed Properties of C22H25NO9S)

Ethyl 3,4,6-tri-O-acetyl-2-deoxy-2-phthalimido-β-D-thioglucopyranoside(cas: 99409-32-2) belongs to indole.The indole subunit is an almost ubiquitous component of biologically active natural products, and its study has been the focus of research for decades.Computed Properties of C22H25NO9SThey are capable of binding to a variety of receptors with high affinity and thus have applications in a wide range of therapeutic areas. Due to this activity, the indole ring system has become an important component or intermediate in the synthesis of heterocycles.

Referemce:
Indole alkaloid derivatives as building blocks of natural products from Bacillus thuringiensis and Bacillus velezensis and their antibacterial and antifungal activity study,
Preparation of Indole Containing Building Blocks for the Regiospecific Construction of Indole Appended Pyrazoles and Pyrroles

SDS of cas: 99409-32-2On November 18, 2000 ,《Determination of the absolute configuration of sulfinyl glycosides: the role of the exo-anomeric effect》 appeared in Tetrahedron Letters. The author of the article were Khiar, N.. The article conveys some information:

The diastereoselective synthesis and conformational study of α- and β-ethylsulfinyl glycosides have been studied. It was found that while β-(SS)-sulfinyl glycosides are flexible β-(RS)-sulfinyl glycosides exists in a major conformation stabilized by the exo-anomeric effect. The generality of the hyper-conjugative delocalization gives rise to a general rule for the determination of the absolute configuration of sulfinyl glycosides by 1H or 13C NMR spectroscopy without need of chem. shift reagents. After reading the article, we found that the author used Ethyl 3,4,6-tri-O-acetyl-2-deoxy-2-phthalimido-β-D-thioglucopyranoside(cas: 99409-32-2SDS of cas: 99409-32-2)

Ethyl 3,4,6-tri-O-acetyl-2-deoxy-2-phthalimido-β-D-thioglucopyranoside(cas: 99409-32-2) belongs to indole.The indole subunit is an almost ubiquitous component of biologically active natural products, and its study has been the focus of research for decades.SDS of cas: 99409-32-2They are capable of binding to a variety of receptors with high affinity and thus have applications in a wide range of therapeutic areas. Due to this activity, the indole ring system has become an important component or intermediate in the synthesis of heterocycles.

Referemce:
Indole alkaloid derivatives as building blocks of natural products from Bacillus thuringiensis and Bacillus velezensis and their antibacterial and antifungal activity study,
Preparation of Indole Containing Building Blocks for the Regiospecific Construction of Indole Appended Pyrazoles and Pyrroles

Lonn, Hans published an article in Carbohydrate Research. The title of the article was 《Synthesis of a tri- and a heptasaccharide which contain α-L-fucopyranosyl groups and are part of the complex type of carbohydrate moiety of glycoproteins》.Formula: C22H25NO9S The author mentioned the following in the article:

Me triflate-promoted condensation of Et 4,6-O-benzylidene-2-deoxy-2-phthalimido-1-thio-3-O-(2,3,4-tri-O-benzyl-α-L-fucopyranosyl)-β-D-glucopyranoside with benzyl 3,4,6-tri-O-benzyl-α-D-mannopyranoside and with benzyl 2,4-di-O-benzyl-3,6-di-O-(3,4,6-tri-O-benzyl-α-D-mannopyranosyl)-α-D-mannopyranoside gave a trisaccharide and a heptasaccharide derivative, resp. The trisaccharide α-L-Fucp-(1→3)-β-D-GlcpNAc-(1→2)-D-Man and the heptasaccharide I, which are parts of the complex type of glycoproteins, were obtained by removal of the protecting groups and N-acetylation. The results came from multiple reactions, including the reaction of Ethyl 3,4,6-tri-O-acetyl-2-deoxy-2-phthalimido-β-D-thioglucopyranoside(cas: 99409-32-2Formula: C22H25NO9S)

Ethyl 3,4,6-tri-O-acetyl-2-deoxy-2-phthalimido-β-D-thioglucopyranoside(cas: 99409-32-2) belongs to indole.The indole subunit is an almost ubiquitous component of biologically active natural products, and its study has been the focus of research for decades.Formula: C22H25NO9SThey are capable of binding to a variety of receptors with high affinity and thus have applications in a wide range of therapeutic areas.

Referemce:
Indole alkaloid derivatives as building blocks of natural products from Bacillus thuringiensis and Bacillus velezensis and their antibacterial and antifungal activity study,
Preparation of Indole Containing Building Blocks for the Regiospecific Construction of Indole Appended Pyrazoles and Pyrroles

Reference of Ethyl 3,4,6-tri-O-acetyl-2-deoxy-2-phthalimido-β-D-thioglucopyranosideOn June 1, 1986, Fugedi, Peter; Garegg, Per J. published an article in Carbohydrate Research. The article was 《A novel promoter for the efficient construction of 1,2-trans linkages in glycoside synthesis, using thioglycosides as glycosyl donors》. The article mentions the following:

Dimethyl(methylthio)sulfonium triflate (I) was used as a promoter for the activation of anomeric thioalkyl (aryl) groups in glycoside synthesis for the construction of 1,2-trans-glycosidic linkages in (1→2), (1→3), (1→4), and (1→6)-linked disaccharides. For example, Me 2,3,4,6-tetra-O-benzoyl-1-thio-β-D-glucopyranoside was treated with 1,2,3,4-tetra-O-benzoyl-β-D-glucopyranose and I in CH2Cl2 in the presence of 4 Å mol. sieve 1 g at 20° to give 92% 1,2,3,4-tetra-O-benzoyl-6-O-(2,3,4,6-tetra-O-benzoyl-β-D-glucopyranosyl)-β-D-glucopyranose. After reading the article, we found that the author used Ethyl 3,4,6-tri-O-acetyl-2-deoxy-2-phthalimido-β-D-thioglucopyranoside(cas: 99409-32-2Reference of Ethyl 3,4,6-tri-O-acetyl-2-deoxy-2-phthalimido-β-D-thioglucopyranoside)

Ethyl 3,4,6-tri-O-acetyl-2-deoxy-2-phthalimido-β-D-thioglucopyranoside(cas: 99409-32-2) belongs to indole.The indole subunit is an almost ubiquitous component of biologically active natural products, and its study has been the focus of research for decades.Reference of Ethyl 3,4,6-tri-O-acetyl-2-deoxy-2-phthalimido-β-D-thioglucopyranosideThey are capable of binding to a variety of receptors with high affinity and thus have applications in a wide range of therapeutic areas.

Referemce:
Indole alkaloid derivatives as building blocks of natural products from Bacillus thuringiensis and Bacillus velezensis and their antibacterial and antifungal activity study,
Preparation of Indole Containing Building Blocks for the Regiospecific Construction of Indole Appended Pyrazoles and Pyrroles

Takeuchi, Kazuya; Tamura, Takayuki; Mukaiyama, Teruaki published an article on February 5 ,2000. The article was titled 《The trityl tetrakis(pentafluorophenyl)borate catalyzed stereoselective glycosylation using new glycosyl donor, 3,4,6-tri-O-benzyl-2-O-p-toluoyl-β-D-glucopyranosyl phenylcarbonate》, and you may find the article in Chemistry Letters.Application of 99409-32-2 The information in the text is summarized as follows:

The trityl tetrakis(pentafluorophenyl)borate [TrB(C6F5)4] catalyzed stereoselective synthesis of various disaccharides was successfully carried out by treating a new 2-O-acyl-protected glycosyl donor, 3,4,6-tri-O-benzyl-2-O-p-toluoyl-β-D-glucopyranosyl phenylcarbonate, with several glycosyl acceptors, thioglycosides, affording the corresponding disaccharides in high yields. The results came from multiple reactions, including the reaction of Ethyl 3,4,6-tri-O-acetyl-2-deoxy-2-phthalimido-β-D-thioglucopyranoside(cas: 99409-32-2Application of 99409-32-2)

Ethyl 3,4,6-tri-O-acetyl-2-deoxy-2-phthalimido-β-D-thioglucopyranoside(cas: 99409-32-2) belongs to indole.The indole subunit is an almost ubiquitous component of biologically active natural products, and its study has been the focus of research for decades.Application of 99409-32-2They are capable of binding to a variety of receptors with high affinity and thus have applications in a wide range of therapeutic areas.

Referemce:
Indole alkaloid derivatives as building blocks of natural products from Bacillus thuringiensis and Bacillus velezensis and their antibacterial and antifungal activity study,
Preparation of Indole Containing Building Blocks for the Regiospecific Construction of Indole Appended Pyrazoles and Pyrroles

HPLC of Formula: 99409-32-2On June 5, 2000, Takeuchi, Kazuya; Tamura, Takayuki; Jona, Hideki; Mukaiyama, Teruaki published an article in Chemistry Letters. The article was 《A novel activating agents of “”disarmed”” thioglycosides, combination of trityl tetrakis(pentafluorophenyl)borate, iodine and 2,3-dichloro-5,6-dicyano-p-benzoquinone (DDQ)》. The article mentions the following:

A combined use of trityl tetrakis(pentafluorophenyl) borate [TrB(C6F5)4], iodine (I2) and 2,3-dichloro-5,6-dicyano-p-benzoquinone (DDQ) effectively activates “”disarmed”” thioglycosides to afford the corresponding disaccharides in high yields on treatment with several glycosyl acceptors. The results came from multiple reactions, including the reaction of Ethyl 3,4,6-tri-O-acetyl-2-deoxy-2-phthalimido-β-D-thioglucopyranoside(cas: 99409-32-2HPLC of Formula: 99409-32-2)

Ethyl 3,4,6-tri-O-acetyl-2-deoxy-2-phthalimido-β-D-thioglucopyranoside(cas: 99409-32-2) belongs to indole.The indole subunit is an almost ubiquitous component of biologically active natural products, and its study has been the focus of research for decades.HPLC of Formula: 99409-32-2They are capable of binding to a variety of receptors with high affinity and thus have applications in a wide range of therapeutic areas. Due to this activity, the indole ring system has become an important component or intermediate in the synthesis of heterocycles.

Referemce:
Indole alkaloid derivatives as building blocks of natural products from Bacillus thuringiensis and Bacillus velezensis and their antibacterial and antifungal activity study,
Preparation of Indole Containing Building Blocks for the Regiospecific Construction of Indole Appended Pyrazoles and Pyrroles

Dan, Akihito; Ito, Yukishige; Ogawa, Tomoya published their research in Carbohydrate Letters on February 29 ,1996. The article was titled 《An efficient synthetic route to bisecting N-acetylglucosamine containing asparagine-linked glycan》.Related Products of 99409-32-2 The article contains the following contents:

A fully stereocontrolled and concise synthetic route to bisecting GlcNAc-containing oligosaccharide is described. The pentasaccharide, which was synthesized previously, by p-methoxybenzyl-assisted β-mannosidation as the key transformation, was reacted with N-phthaloyl-protected glucosamine donor. The desired product obtained was further deprotected into oligosaccharide I, which corresponds to the hexasaccharide region of bisecting GlcNAc-containing Asn-linked glycans. In the experimental materials used by the author, we found Ethyl 3,4,6-tri-O-acetyl-2-deoxy-2-phthalimido-β-D-thioglucopyranoside(cas: 99409-32-2Related Products of 99409-32-2)

Ethyl 3,4,6-tri-O-acetyl-2-deoxy-2-phthalimido-β-D-thioglucopyranoside(cas: 99409-32-2) belongs to indole.The indole subunit is an almost ubiquitous component of biologically active natural products, and its study has been the focus of research for decades.Related Products of 99409-32-2They are capable of binding to a variety of receptors with high affinity and thus have applications in a wide range of therapeutic areas.

Referemce:
Indole alkaloid derivatives as building blocks of natural products from Bacillus thuringiensis and Bacillus velezensis and their antibacterial and antifungal activity study,
Preparation of Indole Containing Building Blocks for the Regiospecific Construction of Indole Appended Pyrazoles and Pyrroles

Ellervik, Ulf; Magnusson, Goeran published an article on January 11 ,1996. The article was titled 《Glycosylation with N-Troc-protected glycosyl donors》, and you may find the article in Carbohydrate Research.Safety of Ethyl 3,4,6-tri-O-acetyl-2-deoxy-2-phthalimido-β-D-thioglucopyranoside The information in the text is summarized as follows:

N-troc-protected (Troc = 2,2,2-trichloroethoxycarbonyl) glucosamine and galactosamine glycosyl donors, e.g. I (R1,R2 = H, OAc), (1-O-acetyl sugar, bromo sugar, and thioglycoside) were compared with the corresponding N-Phth-protected derivatives II (R1,R2 = H, OAc)in glycosylations of 2-(trimethylsilyl)ethanol, 2-bromoethanol, Me 3-mercaptopropionate, N-Fmoc-protected serine, and 2-(trimethylsilyl)ethyl 6-O-benzyl-2-deoxy-2-phthalimido-β-D-glucopyranoside. The N-Troc-protected donors gave pure β-glycosides in somewhat higher yields than the N-Phth-protected counterparts. The N-Troc protecting group can be removed by reduction with zinc, which allows selective N-deprotection in oligosaccharides containing both N-Troc and N-Phth groups. The results came from multiple reactions, including the reaction of Ethyl 3,4,6-tri-O-acetyl-2-deoxy-2-phthalimido-β-D-thioglucopyranoside(cas: 99409-32-2Safety of Ethyl 3,4,6-tri-O-acetyl-2-deoxy-2-phthalimido-β-D-thioglucopyranoside)

Ethyl 3,4,6-tri-O-acetyl-2-deoxy-2-phthalimido-β-D-thioglucopyranoside(cas: 99409-32-2) belongs to indole.The indole subunit is an almost ubiquitous component of biologically active natural products, and its study has been the focus of research for decades.Safety of Ethyl 3,4,6-tri-O-acetyl-2-deoxy-2-phthalimido-β-D-thioglucopyranosideThey are capable of binding to a variety of receptors with high affinity and thus have applications in a wide range of therapeutic areas.

Referemce:
Indole alkaloid derivatives as building blocks of natural products from Bacillus thuringiensis and Bacillus velezensis and their antibacterial and antifungal activity study,
Preparation of Indole Containing Building Blocks for the Regiospecific Construction of Indole Appended Pyrazoles and Pyrroles

The author of 《Iodonium ion-promoted reactions at the anomeric center. II. An efficient thioglycoside-mediated approach toward the formation of 1,2-trans-linked glycosides and glycosidic esters》 were Veeneman, G. H.; Van Leeuwen, S. H.; Van Boom, J. H.. And the article was published in Tetrahedron Letters in 1990. Category: indole-building-block The author mentioned the following in the article:

N-Iodosuccinimide (I) in the presence of an organic acid was effective for the activation of fully acylated thioglycosides leading to 1,2-trans linked esters. For example, tetrabenzoylthiogalactopyranoside II (R = EtS) was treated with I and MeOCH2CO2H in Et2O-ClCH2CH2Cl to give 98% II (R = MeOCH2CO2). On the other hand, I together with a catalytic amount of trifluoromethanesulfonic acid was very convenient for the rapid, high-yielding and stereoselective (1,2-trans) glycosidation of esterified thioglycosides with glycosyl acceptors, e.g., III, to give title compds, e.g., IV.Ethyl 3,4,6-tri-O-acetyl-2-deoxy-2-phthalimido-β-D-thioglucopyranoside(cas: 99409-32-2Category: indole-building-block) was used in this study.

Ethyl 3,4,6-tri-O-acetyl-2-deoxy-2-phthalimido-β-D-thioglucopyranoside(cas: 99409-32-2) belongs to indole.The indole subunit is an almost ubiquitous component of biologically active natural products, and its study has been the focus of research for decades.Category: indole-building-blockThey are capable of binding to a variety of receptors with high affinity and thus have applications in a wide range of therapeutic areas.

Referemce:
Indole alkaloid derivatives as building blocks of natural products from Bacillus thuringiensis and Bacillus velezensis and their antibacterial and antifungal activity study,
Preparation of Indole Containing Building Blocks for the Regiospecific Construction of Indole Appended Pyrazoles and Pyrroles

Garegg, Per J.; Oscarson, Stefan; Tiden, Anna Karin published an article on February 17 ,1992. The article was titled 《Synthesis of p-trifluoroacetamidophenyl 2-acetamido-4-O-(2-acetamido-2-deoxy-β-D-glucopyranosyl)-2-deoxy-β-D-mannopyranosiduronic acid, an artificial antigen corresponding to a disaccharide repeating unit of the capsular polysaccharide of Haemophilus influenzae type e》, and you may find the article in Carbohydrate Research.Category: indole-building-block The information in the text is summarized as follows:

The title compound I was prepared from 4-nitrophenyl 2-azido-4,6-O-benzylidene-2-deoxy-β-D-mannopyranoside via glycosidation of silylated azidodeoxymannopyranoside II with Et 2,4,6-tri-O-acetyl-2-deoxy-2-phthalimido-1-thio-β-D-glucopyranoside (III). After reading the article, we found that the author used Ethyl 3,4,6-tri-O-acetyl-2-deoxy-2-phthalimido-β-D-thioglucopyranoside(cas: 99409-32-2Category: indole-building-block)

Ethyl 3,4,6-tri-O-acetyl-2-deoxy-2-phthalimido-β-D-thioglucopyranoside(cas: 99409-32-2) belongs to indole.The indole subunit is an almost ubiquitous component of biologically active natural products, and its study has been the focus of research for decades.Category: indole-building-blockThey are capable of binding to a variety of receptors with high affinity and thus have applications in a wide range of therapeutic areas.

Referemce:
Indole alkaloid derivatives as building blocks of natural products from Bacillus thuringiensis and Bacillus velezensis and their antibacterial and antifungal activity study,
Preparation of Indole Containing Building Blocks for the Regiospecific Construction of Indole Appended Pyrazoles and Pyrroles