Tag: 400-500

Application of 99409-32-2On September 30, 1992 ,《Efficient conversion of thioglycosides into glycosyl fluorides using dimethyl(methylthio)sulfonium tetrafluoroborate》 was published in Journal of Carbohydrate Chemistry. The article was written by Blomberg, Lennart; Norberg, Thomas. The article contains the following contents:

Alkyl and aryl thioglycosides, e.g., I, were converted in high yield into the corresponding α-glycosyl fluorides, e.g., II, by treatment with dimethyl(methylthio)sulfonium tetrafluoroborate. Glycosidic linkages and most protective groups are not affected by the reaction conditions. Glycosyl fluorides are proposed to be intermediates in glycosylations promoted by dimethyl(methylthio)sulfonium tetrafluoroborate. The experimental part of the paper was very detailed, including the reaction process of Ethyl 3,4,6-tri-O-acetyl-2-deoxy-2-phthalimido-β-D-thioglucopyranoside(cas: 99409-32-2Application of 99409-32-2)

Ethyl 3,4,6-tri-O-acetyl-2-deoxy-2-phthalimido-β-D-thioglucopyranoside(cas: 99409-32-2) belongs to indole.The indole subunit is an almost ubiquitous component of biologically active natural products, and its study has been the focus of research for decades.Application of 99409-32-2They are capable of binding to a variety of receptors with high affinity and thus have applications in a wide range of therapeutic areas. Due to this activity, the indole ring system has become an important component or intermediate in the synthesis of heterocycles.

Referemce:
Indole alkaloid derivatives as building blocks of natural products from Bacillus thuringiensis and Bacillus velezensis and their antibacterial and antifungal activity study,
Preparation of Indole Containing Building Blocks for the Regiospecific Construction of Indole Appended Pyrazoles and Pyrroles

Name: Ethyl 3,4,6-tri-O-acetyl-2-deoxy-2-phthalimido-β-D-thioglucopyranosideOn September 30, 1988 ,《Reductive dephthalimidation: a mild and efficient method for the N-phthalimido deprotection during oligosaccharide synthesis》 was published in Journal of Carbohydrate Chemistry. The article was written by Dasgupta, Falguni; Garegg, Per J.. The article contains the following contents:

NaBH4 cleaves the phthalimido group in suitably protected carbohydrates. Best results are obtained with 8-10 M excess NaBH4. Thus, phthalimidoglucopyranoside I (RR1N = phthalimido) (0.17 mmol) in Me2CHOH-H2O was treated with 1.74 mmol NaBH4 (4 lot added over 4-6 h at room temperature). The product was acetylated with AcOH-pyridine to give 77% I (RR1N = AcNH). The results came from multiple reactions, including the reaction of Ethyl 3,4,6-tri-O-acetyl-2-deoxy-2-phthalimido-β-D-thioglucopyranoside(cas: 99409-32-2Name: Ethyl 3,4,6-tri-O-acetyl-2-deoxy-2-phthalimido-β-D-thioglucopyranoside)

Ethyl 3,4,6-tri-O-acetyl-2-deoxy-2-phthalimido-β-D-thioglucopyranoside(cas: 99409-32-2) belongs to indole.The indole subunit is an almost ubiquitous component of biologically active natural products, and its study has been the focus of research for decades.Name: Ethyl 3,4,6-tri-O-acetyl-2-deoxy-2-phthalimido-β-D-thioglucopyranosideThey are capable of binding to a variety of receptors with high affinity and thus have applications in a wide range of therapeutic areas. Due to this activity, the indole ring system has become an important component or intermediate in the synthesis of heterocycles.

Referemce:
Indole alkaloid derivatives as building blocks of natural products from Bacillus thuringiensis and Bacillus velezensis and their antibacterial and antifungal activity study,
Preparation of Indole Containing Building Blocks for the Regiospecific Construction of Indole Appended Pyrazoles and Pyrroles

Related Products of 99409-32-2On September 30, 1998 ,《Synthesis of the tetrasaccharide repeating unit of the antigen from Escherichia coli O126 as its methyl glycoside》 was published in Journal of Carbohydrate Chemistry. The article was written by Misra, Anup Kumar; Roy, Nirmolendu. The article contains the following contents:

The tetrasaccharide repeating unit of the antigen from E. coli O126 has been synthesized as its Me glycoside by sequential addition of monosaccharide derivatives The formation of the β-mannosidic linkage was achieved by Swern oxidation of the glucose derivative followed by reduction of the product with sodium borohydride. After reading the article, we found that the author used Ethyl 3,4,6-tri-O-acetyl-2-deoxy-2-phthalimido-β-D-thioglucopyranoside(cas: 99409-32-2Related Products of 99409-32-2)

Ethyl 3,4,6-tri-O-acetyl-2-deoxy-2-phthalimido-β-D-thioglucopyranoside(cas: 99409-32-2) belongs to indole.The indole subunit is an almost ubiquitous component of biologically active natural products, and its study has been the focus of research for decades.Related Products of 99409-32-2They are capable of binding to a variety of receptors with high affinity and thus have applications in a wide range of therapeutic areas. Due to this activity, the indole ring system has become an important component or intermediate in the synthesis of heterocycles.

Referemce:
Indole alkaloid derivatives as building blocks of natural products from Bacillus thuringiensis and Bacillus velezensis and their antibacterial and antifungal activity study,
Preparation of Indole Containing Building Blocks for the Regiospecific Construction of Indole Appended Pyrazoles and Pyrroles

Jana, Manas; Ghosh, Anirban; Santra, Abhishek; Kar, Rajiv Kumar; Misra, Anup Kumar; Bhunia, Anirban published an article in Journal of Colloid and Interface Science. The title of the article was 《Synthesis of novel muramic acid derivatives and their interaction with lysozyme: Action of lysozyme revisited》.Name: Ethyl 3,4,6-tri-O-acetyl-2-deoxy-2-phthalimido-β-D-thioglucopyranoside The author mentioned the following in the article:

The interaction of lysozyme with the N-acetylmuramic acid (NAM) and N-acetylglucosamine (NAG) unit of peptidoglycan (PGN) polymer of the bacterial cell wall is of immense importance to understand the mechanism of lysozyme on PGN. The synthesis of three novel NAM derivatives containing fused oxazinone ring to the NAM moiety has been achieved. The synthesized compounds were evaluated for their potential as a glycomimetic acceptor of lysozyme using different biophys. and computational methods such as 1H NMR, STD NMR, DOSY and Mol. docking. Novel modified muramic acid derivatives have been synthesized in excellent yield containing fused cyclooxazine ring embedded on the muramic acid moiety using a newly developed hydrazinolysis reaction condition. From various biophys. studies, it has been established that the compound containing endo modified muramic acid moiety (compound 1) shows significant binding property for the lysozyme while the other isomer (compound 2) did not bind to the lysozyme. The catalytic residues Glu35 and Asp52 were found to be in the close proximity for the active mol. which justifies the selectivity of this mol. in conjunction to lysozyme enzymic activity. In the part of experimental materials, we found many familiar compounds, such as Ethyl 3,4,6-tri-O-acetyl-2-deoxy-2-phthalimido-β-D-thioglucopyranoside(cas: 99409-32-2Name: Ethyl 3,4,6-tri-O-acetyl-2-deoxy-2-phthalimido-β-D-thioglucopyranoside)

Ethyl 3,4,6-tri-O-acetyl-2-deoxy-2-phthalimido-β-D-thioglucopyranoside(cas: 99409-32-2) belongs to indole.The indole subunit is an almost ubiquitous component of biologically active natural products, and its study has been the focus of research for decades.Name: Ethyl 3,4,6-tri-O-acetyl-2-deoxy-2-phthalimido-β-D-thioglucopyranosideThey are capable of binding to a variety of receptors with high affinity and thus have applications in a wide range of therapeutic areas. Due to this activity, the indole ring system has become an important component or intermediate in the synthesis of heterocycles.

Referemce:
Indole alkaloid derivatives as building blocks of natural products from Bacillus thuringiensis and Bacillus velezensis and their antibacterial and antifungal activity study,
Preparation of Indole Containing Building Blocks for the Regiospecific Construction of Indole Appended Pyrazoles and Pyrroles

《Toward Fully Synthetic Homogeneous β-Human Follicle-Stimulating Hormone (β-hFSH) with a Biantennary N-Linked Dodecasaccharide. Synthesis of β-hFSH with Chitobiose Units at the Natural Linkage Sites》 was written by Nagorny, Pavel; Fasching, Bernhard; Li, Xuechen; Chen, Gong; Aussedat, Baptiste; Danishefsky, Samuel J.. Recommanded Product: Ethyl 3,4,6-tri-O-acetyl-2-deoxy-2-phthalimido-β-D-thioglucopyranoside And the article was included in Journal of the American Chemical Society on April 29 ,2009. The article conveys some information:

A highly convergent synthesis of the sialic acid-rich biantennary N-linked glycan found in human glycoprotein hormones and its use in the synthesis of a fragment derived from the β-domain of human FSH (hFSH) are described. The synthesis highlights the use of the Sinay radical glycosidation protocol for the simultaneous installation of both biantennary side-chains of the dodecasaccharide as well as the use of glycal chem. to construct the tetrasaccharide core in an efficient manner. The synthetic glycan was used to prepare the glycosylated 20-27aa domain of the β-subunit of hFSH under a Lansbury aspartylation protocol. The proposed strategy for incorporating the prepared N-linked dodecasaccharide-containing 20-27aa domain into β-hFSH subunit was validated in the context of a model system, providing protected β-hFSH subunit functionalized with chitobiose at positions 7 and 24. The experimental part of the paper was very detailed, including the reaction process of Ethyl 3,4,6-tri-O-acetyl-2-deoxy-2-phthalimido-β-D-thioglucopyranoside(cas: 99409-32-2Recommanded Product: Ethyl 3,4,6-tri-O-acetyl-2-deoxy-2-phthalimido-β-D-thioglucopyranoside)

Ethyl 3,4,6-tri-O-acetyl-2-deoxy-2-phthalimido-β-D-thioglucopyranoside(cas: 99409-32-2) belongs to indole.The indole subunit is an almost ubiquitous component of biologically active natural products, and its study has been the focus of research for decades.Recommanded Product: Ethyl 3,4,6-tri-O-acetyl-2-deoxy-2-phthalimido-β-D-thioglucopyranosideThey are capable of binding to a variety of receptors with high affinity and thus have applications in a wide range of therapeutic areas. Due to this activity, the indole ring system has become an important component or intermediate in the synthesis of heterocycles.

Referemce:
Indole alkaloid derivatives as building blocks of natural products from Bacillus thuringiensis and Bacillus velezensis and their antibacterial and antifungal activity study,
Preparation of Indole Containing Building Blocks for the Regiospecific Construction of Indole Appended Pyrazoles and Pyrroles

Silwanis, Basim Azmy; El-Sokkary, Ramadan I.; Nashed, Mina A.; Paulsen, Hans published their research in Journal of Carbohydrate Chemistry on December 31 ,1991. The article was titled 《A comparison in the efficiency of six standard 2-amino-2-deoxyglucosyl donors for the synthesis of (2-deoxy-2-phthalimido-β-D-glucopyranosyl) (1→4)-β-D-glucopyranosides》.Recommanded Product: Ethyl 3,4,6-tri-O-acetyl-2-deoxy-2-phthalimido-β-D-thioglucopyranoside The article contains the following contents:

A systematic study is presented for the most common methods used for the preparation of the disaccharide benzyl O-(3,4,6-tri-O-acetyl-2-deoxy-2-phthalimido-β-D-glucopyranosyl)-(1→4)-3,6-di-O-benzoyl-2-deoxy-2-phthalimido-β-D-glucopyranoside from standard 2-amino-2-deoxyglucopyranosyl donors, e.g. I (R = Br, Cl, F, OAc, OC(NH)CCl3, SEt, R1 = phthalimido), and benzyl 3,6-di-O-benzoyl-2-deoxy-2-phthalimido-β-D-glucopyranoside as an acceptor. It was found that the highest yield was obtained when the trichloroacetimidate derivative I was coupled to the 4 position of acceptor 7. After reading the article, we found that the author used Ethyl 3,4,6-tri-O-acetyl-2-deoxy-2-phthalimido-β-D-thioglucopyranoside(cas: 99409-32-2Recommanded Product: Ethyl 3,4,6-tri-O-acetyl-2-deoxy-2-phthalimido-β-D-thioglucopyranoside)

Ethyl 3,4,6-tri-O-acetyl-2-deoxy-2-phthalimido-β-D-thioglucopyranoside(cas: 99409-32-2) belongs to indole.The indole subunit is an almost ubiquitous component of biologically active natural products, and its study has been the focus of research for decades.Recommanded Product: Ethyl 3,4,6-tri-O-acetyl-2-deoxy-2-phthalimido-β-D-thioglucopyranosideThey are capable of binding to a variety of receptors with high affinity and thus have applications in a wide range of therapeutic areas. Due to this activity, the indole ring system has become an important component or intermediate in the synthesis of heterocycles.

Referemce:
Indole alkaloid derivatives as building blocks of natural products from Bacillus thuringiensis and Bacillus velezensis and their antibacterial and antifungal activity study,
Preparation of Indole Containing Building Blocks for the Regiospecific Construction of Indole Appended Pyrazoles and Pyrroles

Liu, Xiao Gao; Jain, Rakesh K.; Saha, Raj; Matta, Khushi L. published an article in Bioorganic & Medicinal Chemistry Letters. The title of the article was 《Synthesis of Gal-β-(1→4)-6-O-SO3Na-GlcNAc-β-(1→6)-Man-α-OR as a part of glycoprotein (gp) 120》.Safety of Ethyl 3,4,6-tri-O-acetyl-2-deoxy-2-phthalimido-β-D-thioglucopyranoside The author mentioned the following in the article:

The synthesis of Gal-β-(1→4)-6-O-SO2Na-GlcNAc-β-(1→6)-Man-α-OR (as a part of gp 120) containing an anomeric p-nitrophenyl group was accomplished via stereoselective glycosidation of Et 3,4,6-tri-O-chloroacetyl-2-deoxy-2-phthalimido-1-thio-β-D-glucopyranoside. Title oligosaccharide can act as acceptor of α-2,3-sialyltransferase to give NeuAcα-(2→3)-Gal-β-(1→4)-6-O-SO2Na-GlcNAc-β-(1→6)-Man-α-OR which occurs as a part of gp 120. In the part of experimental materials, we found many familiar compounds, such as Ethyl 3,4,6-tri-O-acetyl-2-deoxy-2-phthalimido-β-D-thioglucopyranoside(cas: 99409-32-2Safety of Ethyl 3,4,6-tri-O-acetyl-2-deoxy-2-phthalimido-β-D-thioglucopyranoside)

Ethyl 3,4,6-tri-O-acetyl-2-deoxy-2-phthalimido-β-D-thioglucopyranoside(cas: 99409-32-2) belongs to indole.The indole subunit is an almost ubiquitous component of biologically active natural products, and its study has been the focus of research for decades.Safety of Ethyl 3,4,6-tri-O-acetyl-2-deoxy-2-phthalimido-β-D-thioglucopyranosideThey are capable of binding to a variety of receptors with high affinity and thus have applications in a wide range of therapeutic areas.

Referemce:
Indole alkaloid derivatives as building blocks of natural products from Bacillus thuringiensis and Bacillus velezensis and their antibacterial and antifungal activity study,
Preparation of Indole Containing Building Blocks for the Regiospecific Construction of Indole Appended Pyrazoles and Pyrroles

In 1991,NATO ASI Series, Series H: Cell Biology included an article by Peters, J. L.; Wesselius, J. C.; Georghiou, K. C.; Kendrick, R. E.; Van Tuinen, A.; Koornneef, M.. Product Details of 99409-32-2. The article was titled 《The physiology of photomorphogenetic tomato mutants》. The information in the text is summarized as follows:

A review with 37 references Photomorphogenesis of higher plants is a complex process resulting from the co-action of at least 3 different photoreceptors: phytochrome, a blue light (B)/UV-A photoreceptor (cryptochrome) and a UV-B photoreceptor. The existence of multiple photoreceptor types, e.g. type I (PI) or light-labile phytochrome and type II (PII) or light-stable phytochrome, adds to the complexity. The assignment of specific functions to the distinct mol. species of the photoreceptor is therefore being studied with the aid of photomorphogenetic mutants in which certain parts of the morphogenetic pathway are eliminated or altered. The relevance of the changed part in the mutant is directly indicated by its difference in response compared to its isogenic wild type. Mutants can be found (isolated) from natural populations or varieties (cultivars) or more efficiently after mutagenic treatment: using e.g. chems., irradiation; somaclonal variation; transposon insertion; transformation; introduction of antisense RNA. Photomorphogenetic mutants can be divided into three groups: photoreceptor mutants, lacking the photoreceptor or containing a modified photoreceptor which is non-functional; transduction chain mutants and response mutants. The first two will be pleiotropic for all responses regulated by the photoreceptor, while the latter are modified with respect to particular responses. Tomato (Lycospersicon esculentum) has several features which make it suitable for genetic anal. It is widely studied since it is a crop species of economic importance and many mutants are available. In addition it has a relatively small genome, is diploid with 12 chromosomes, is self pollinating, individual plants producing a large number (≈2000) of relatively large seeds which result in seedlings suitable for physiol. anal. and it is amenable for Agrobacterium-mediated transformation. Mutants of tomato which are important for the study of photomorphogenesis are discussed. In the experiment, the researchers used Ethyl 3,4,6-tri-O-acetyl-2-deoxy-2-phthalimido-β-D-thioglucopyranoside(cas: 99409-32-2Product Details of 99409-32-2)

Ethyl 3,4,6-tri-O-acetyl-2-deoxy-2-phthalimido-β-D-thioglucopyranoside(cas: 99409-32-2) belongs to indole.The indole subunit is an almost ubiquitous component of biologically active natural products, and its study has been the focus of research for decades.Product Details of 99409-32-2They are capable of binding to a variety of receptors with high affinity and thus have applications in a wide range of therapeutic areas. Due to this activity, the indole ring system has become an important component or intermediate in the synthesis of heterocycles.

Referemce:
Indole alkaloid derivatives as building blocks of natural products from Bacillus thuringiensis and Bacillus velezensis and their antibacterial and antifungal activity study,
Preparation of Indole Containing Building Blocks for the Regiospecific Construction of Indole Appended Pyrazoles and Pyrroles

Chery, Florence; Cassel, Stephanie; Wessel, Hans Peter; Rollin, Patrick published an article on January 31 ,2002. The article was titled 《Synthesis of anomeric sulfimides and their use as a new family of glycosyl donors》, and you may find the article in European Journal of Organic Chemistry.Recommanded Product: Ethyl 3,4,6-tri-O-acetyl-2-deoxy-2-phthalimido-β-D-thioglucopyranoside The information in the text is summarized as follows:

We introduce a convenient synthesis of anomeric sulfimides, the ability of which to act as glycosyl donors has been tested with various thiophilic reagents and acceptors. The experimental process involved the reaction of Ethyl 3,4,6-tri-O-acetyl-2-deoxy-2-phthalimido-β-D-thioglucopyranoside(cas: 99409-32-2Recommanded Product: Ethyl 3,4,6-tri-O-acetyl-2-deoxy-2-phthalimido-β-D-thioglucopyranoside)

Ethyl 3,4,6-tri-O-acetyl-2-deoxy-2-phthalimido-β-D-thioglucopyranoside(cas: 99409-32-2) belongs to indole.The indole subunit is an almost ubiquitous component of biologically active natural products, and its study has been the focus of research for decades.Recommanded Product: Ethyl 3,4,6-tri-O-acetyl-2-deoxy-2-phthalimido-β-D-thioglucopyranosideThey are capable of binding to a variety of receptors with high affinity and thus have applications in a wide range of therapeutic areas.

Referemce:
Indole alkaloid derivatives as building blocks of natural products from Bacillus thuringiensis and Bacillus velezensis and their antibacterial and antifungal activity study,
Preparation of Indole Containing Building Blocks for the Regiospecific Construction of Indole Appended Pyrazoles and Pyrroles

Electric Literature of C22H25NO9SOn October 22, 2001 ,《Efficient synthesis of lactosaminylated core-2 O-glycans》 was published in Bioorganic & Medicinal Chemistry Letters. The article was written by Misra, A. K.; Fukuda, M.; Hindsgaul, O.. The article contains the following contents:

A series of lactosaminylated oligosaccharides found in mucin type O-glycans was synthesized using a generalized block strategy. The synthesis involved the addition of a protected lactosamine donor to a partially protected T-disaccharide derivative The nonreducing galactose residues of the deblocked oligosaccharide products could be removed by β-galactosidase from jack bean to produce the corresponding GlcNAc terminated compounds A series of tri- to hexasaccharides was thus efficiently produced. In addition to this study using Ethyl 3,4,6-tri-O-acetyl-2-deoxy-2-phthalimido-β-D-thioglucopyranoside, there are many other studies that have used Ethyl 3,4,6-tri-O-acetyl-2-deoxy-2-phthalimido-β-D-thioglucopyranoside(cas: 99409-32-2Electric Literature of C22H25NO9S) was used in this study.

Ethyl 3,4,6-tri-O-acetyl-2-deoxy-2-phthalimido-β-D-thioglucopyranoside(cas: 99409-32-2) belongs to indole.The indole subunit is an almost ubiquitous component of biologically active natural products, and its study has been the focus of research for decades.Electric Literature of C22H25NO9SThey are capable of binding to a variety of receptors with high affinity and thus have applications in a wide range of therapeutic areas. Due to this activity, the indole ring system has become an important component or intermediate in the synthesis of heterocycles.

Referemce:
Indole alkaloid derivatives as building blocks of natural products from Bacillus thuringiensis and Bacillus velezensis and their antibacterial and antifungal activity study,
Preparation of Indole Containing Building Blocks for the Regiospecific Construction of Indole Appended Pyrazoles and Pyrroles