With the rapid development and complex challenges of chemical substances, new drug synthesis pathways are usually the most effective.700-06-1,Indole-3-Carbinol,as a common compound, the synthetic route is as follows.,700-06-1
20 mL of a tubular reactor was charged with 3-indole methanol (73.5 mg, 0.50 mmol), triethyl phosphite(166.0 mg, 1.0 mmol, 2.0 equiv.) And tetrabutylammonium iodide (9.3 mg, 0.025 mmol, 5 mol%),Vacuum nitrogen, and then heated to 120 C for 24 h under solvent-free conditions. After the TLC monitoring reaction was complete, the product was purified by column chromatography and the yield was 83%.
The synthetic route of 700-06-1 has been constantly updated, and we look forward to future research findings.
Reference£º
Patent; Wenzhou University; Xu Qing; Ma Xiantao; Su Chenliang; Han Libiao; (11 pag.)CN106543221; (2017); A;,
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