Tag: M.W:200-300

The preparation of ester heterocycles mostly uses heteroatoms as nucleophilic sites, which are achieved by intramolecular substitution or addition reactions. Compound: Nickel(II) chloride ethylene glycol dimethyl ether complex( cas:29046-78-4 ) is researched.SDS of cas: 29046-78-4.Li, Haoyang; Long, Jiao; Li, Yuqiang; Wang, Wang; Pang, Hailiang; Yin, Guoyin published the article 《Nickel-Catalyzed Regioselective Arylboration of Conjugated Dienes》 about this compound( cas:29046-78-4 ) in European Journal of Organic Chemistry. Keywords: allyl alc arylated preparation arylboration conjugated diene oxidation. Let’s learn more about this compound (cas:29046-78-4).

The nickel-catalyzed arylboration of conjugated dienes CH2:CRCH:CH2 with aryl bromides ArBr and B2pin2, yielding (E)-ArCH2CR:CHCH2OH after oxidation, is reported. Good 1,4-regioselectivity and (E)-stereoselectivity were obtained using isoprene, together with very good 1,2-regioselectivity and (E)-stereoselectivity using 1-arylbutadienes. The high reactivity and selectivity of this process were dependent on the use of the appropriate nitrogen-based ligand. Moreover, wide functional group tolerance was observed under mild reaction conditions. This protocol provides a path to allyl or homoallyl boronic ester derivatives starting from 1,3-dienes, aryl bromides, and B2pin2. The downstream transformation of allyl boronic esters was also achieved, suggesting a strategy for the diastereoselective 1,2-difunctionalization of isoprene and demonstrating the potential for the synthesis of complex mols.

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Reference:
Indole alkaloid derivatives as building blocks of natural products from Bacillus thuringiensis and Bacillus velezensis and their antibacterial and antifungal activity study,
Preparation of Indole Containing Building Blocks for the Regiospecific Construction of Indole Appended Pyrazoles and Pyrroles

Epoxy compounds usually have stronger nucleophilic ability, because the alkyl group on the oxygen atom makes the bond angle smaller, which makes the lone pair of electrons react more dissimilarly with the electron-deficient system. Compound: Nickel(II) chloride ethylene glycol dimethyl ether complex, is researched, Molecular C4H10Cl2NiO2, CAS is 29046-78-4, about Acyl Radicals from α-Keto Acids Using a Carbonyl Photocatalyst: Photoredox-Catalyzed Synthesis of Ketones.Recommanded Product: Nickel(II) chloride ethylene glycol dimethyl ether complex.

Acyl radicals have been generated from α-keto acids RC(O)C(O)OH (R = Ph, furan-2-yl, Me, etc.) using inexpensive and com. available 2-chloro-thioxanthen-9-one as the photoredox catalyst under visible light illumination. These reactive species added to olefins R1CH=CH(R3)R2 [R1 = H, Me, Ph, 4-fluorophenyl, etc.; R2 = H, Me, C(O)OCH3, C(O)OC2H5; R3 = H, C(O)Ph, Boc, (cyclohexyloxy)carbonyl, C(O)OC2H5] or coupled with aryl halides ArX (Ar = Ph, 6-(trifluoromethyl)pyridin-2-yl, quinolin-3-yl, etc.) via a bipyridyl-stabilized Ni(II) catalyst, enabling easy access to a diverse range of ketones ArC(O)R and RC(O)CH(R1)CH(R3)R2. This reliable, atom-economical, and eco-friendly protocol is compatible with a wide range of functional groups.

After consulting a lot of data, we found that this compound(29046-78-4)Recommanded Product: Nickel(II) chloride ethylene glycol dimethyl ether complex can be used in many types of reactions. And in most cases, this compound has more advantages.

Reference:
Indole alkaloid derivatives as building blocks of natural products from Bacillus thuringiensis and Bacillus velezensis and their antibacterial and antifungal activity study,
Preparation of Indole Containing Building Blocks for the Regiospecific Construction of Indole Appended Pyrazoles and Pyrroles

Most of the natural products isolated at present are heterocyclic compounds, so heterocyclic compounds occupy an important position in the research of organic chemistry. A compound: 29046-78-4, is researched, SMILESS is COCCOC.Cl[Ni]Cl, Molecular C4H10Cl2NiO2Journal, Applied Organometallic Chemistry called Polynuclear (α-diimine) nickel(II) complex as catalyst for ethylene oligomerization, Author is Li, Dan; Ma, Fengmin; Guo, Lijun; Huang, Jin; Zhang, Yu; Li, Feng; Li, Cuiqin, the main research direction is ethylene oligomerization polynuclear diimine nickel complex catalyst synthesis.Computed Properties of C4H10Cl2NiO2.

Late transition metal catalysts with single or multiple active centers have great attention in the ethylene oligomerization application owing to their unique properties. A new polynuclear (α-diimine) nickel(II) complex (PS-Ni complex) bearing the conjugated poly(Schiff-base) ligand (PS-ligand) was synthesized. The structures and the composition of the PS-ligand and the PS-Ni complex were characterized by Fourier transform IR (FTIR) anal., X-ray diffraction (XRD), XPS, SEM, thermogravimetric (TG) anal., NMR (NMR) and gel permeation chromatog. (GPC). The PS-Ni complex was used as precatalyst in ethylene oligomerization combined with methylaluminoxane (MAO) and has good catalytic activity for ethylene oligomerization under mild conditions. Compared with the corresponding mononuclear (α-diimine) nickel(II) complex, the PS-Ni complex showed higher activity of 17.62 × 105 g/(mol Ni·h), and the main products were C4 and C6 olefins in cyclohexane when the dosage of precatalyst was 2μmol, the Al/Ni molar ratio was 500, the ethylene pressure was 0.5 MPa, the reaction time was 60 min, and the reaction temperature was 25°C. The main oligomers were α-olefins, and the selectivity was up to 98.68%, due to the more electron-deficient catalytic centers of the conjugated structure of poly(Schiff-base) ligand.

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Reference:
Indole alkaloid derivatives as building blocks of natural products from Bacillus thuringiensis and Bacillus velezensis and their antibacterial and antifungal activity study,
Preparation of Indole Containing Building Blocks for the Regiospecific Construction of Indole Appended Pyrazoles and Pyrroles

Quality Control of Nickel(II) chloride ethylene glycol dimethyl ether complex. The mechanism of aromatic electrophilic substitution of aromatic heterocycles is consistent with that of benzene. Compound: Nickel(II) chloride ethylene glycol dimethyl ether complex, is researched, Molecular C4H10Cl2NiO2, CAS is 29046-78-4, about Upscaling Photoredox Cross-Coupling Reactions in Batch Using Immersion-Well Reactors. Author is Grimm, Isabelle; Hauer, Simone T.; Schulte, Tim; Wycich, Gina; Collins, Karl D.; Lovis, Kai; Candish, Lisa.

Herein we describe a straightforward approach for the scale-up of photoredox cross-coupling reactions from milligram to multigram scale using immersion-well batch reactors with minimal reoptimization of the reaction conditions. This approach can be applied to both homogeneous and, more significantly, heterogeneous reaction mixtures Furthermore, we have used an immersion-well side-loop reactor to perform a reaction on a 400 mmol scale (86 g of aryl bromide).

After consulting a lot of data, we found that this compound(29046-78-4)Quality Control of Nickel(II) chloride ethylene glycol dimethyl ether complex can be used in many types of reactions. And in most cases, this compound has more advantages.

Reference:
Indole alkaloid derivatives as building blocks of natural products from Bacillus thuringiensis and Bacillus velezensis and their antibacterial and antifungal activity study,
Preparation of Indole Containing Building Blocks for the Regiospecific Construction of Indole Appended Pyrazoles and Pyrroles

Quality Control of Nickel(II) chloride ethylene glycol dimethyl ether complex. The mechanism of aromatic electrophilic substitution of aromatic heterocycles is consistent with that of benzene. Compound: Nickel(II) chloride ethylene glycol dimethyl ether complex, is researched, Molecular C4H10Cl2NiO2, CAS is 29046-78-4, about Photoredox-Catalysis-Modulated, Nickel-Catalyzed Divergent Difunctionalization of Ethylene. Author is Li, Jiesheng; Luo, Yixin; Cheo, Han Wen; Lan, Yu; Wu, Jie.

Herein, the use of ethylene feedstock and com. available aryl halides was demonstrated to accomplish the divergent synthesis of 1,2-diarylethanes, 1,4-diarylbutanes, or 2,3-diarylbutanes in a highly selective fashion through the synergistic combination of nickel and photoredox catalysis. Mechanistic studies suggested that the observed selectivity was due to different active states of Ni(I) and Ni(0) modulated by Ru- and Ir-based photoredox catalysts, resp. The ability to access different organometallic oxidation states via photoredox catalysis promises to inspire new perspectives for synergistic transition-metal-catalyzed divergent synthesis.

After consulting a lot of data, we found that this compound(29046-78-4)Quality Control of Nickel(II) chloride ethylene glycol dimethyl ether complex can be used in many types of reactions. And in most cases, this compound has more advantages.

Reference:
Indole alkaloid derivatives as building blocks of natural products from Bacillus thuringiensis and Bacillus velezensis and their antibacterial and antifungal activity study,
Preparation of Indole Containing Building Blocks for the Regiospecific Construction of Indole Appended Pyrazoles and Pyrroles

Electric Literature of C4H8Br2. Aromatic compounds can be divided into two categories: single heterocycles and fused heterocycles. Compound: 1,4-Dibromobutane, is researched, Molecular C4H8Br2, CAS is 110-52-1, about Pd nanoparticles supported on MOF/ionic liquid system: a heterogeneous catalyst for the C-O bond formation via Ullmann-type reaction. Author is Askari, Saeed; Khodaei, Mohammad Mehdi; Jafarzadeh, Mohammad.

Abstract: Palladium nanoparticles (NPs) are deposited on the supported ionic liquid (IL). The IL is initially supported on zirconium metal-organic framework (i.e., UiO-66-NH2), and subsequently modified with guanidine. It is proposed that the presence of amine groups in the guanidine can efficiently stabilize the NPs. The composite system, UiO-66-NH2-ILPF6–guanidine-Pd NPs, is used for catalyzing a C-O coupling Ullmann reaction. This heterogeneous catalyst exhibited excellent activity for the reaction between Ph halides and phenol derivatives in the absence of an addnl. base, which typically used for deprotonation of phenols. In other words, the counter-anion of the IL acts as a base for this reaction. The catalyst is capable to recover and reuse several times with reasonable activity.

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Reference:
Indole alkaloid derivatives as building blocks of natural products from Bacillus thuringiensis and Bacillus velezensis and their antibacterial and antifungal activity study,
Preparation of Indole Containing Building Blocks for the Regiospecific Construction of Indole Appended Pyrazoles and Pyrroles

So far, in addition to halogen atoms, other non-metallic atoms can become part of the aromatic heterocycle, and the target ring system is still aromatic.Huang, Long; Ji, Tengfei; Rueping, Magnus researched the compound: Nickel(II) chloride ethylene glycol dimethyl ether complex( cas:29046-78-4 ).Reference of Nickel(II) chloride ethylene glycol dimethyl ether complex.They published the article 《Remote Nickel-Catalyzed Cross-Coupling Arylation via Proton-Coupled Electron Transfer-Enabled C-C Bond Cleavage》 about this compound( cas:29046-78-4 ) in Journal of the American Chemical Society. Keywords: aryl ketone preparation; arylcyclic alc preparation photoredo cross coupling arylation nickel photocatalyst. We’ll tell you more about this compound (cas:29046-78-4).

Cross-coupling reactions for carbon-carbon and carbon-heteroatom bond formation are of great importance in modern chem. synthesis. In addition to classical cross-couplings involving preformed or preactivated coupling partners, more recently breakthroughs have been made in the selective, direct coupling of abundant aliphatic carbon-hydrogen bonds using hydrogen atom transfer reactions in which the bond-dissociation energy is the thermodn. driving force. The more challenging carbon-carbon bond activation is still rather underdeveloped due to the bond inertness. Herein, we report a mild and general strategy for the activation of a diverse set of readily available cyclic alcs. for the remote and site-specific arylation of ketones via the combination of photoredox-mediated multisite concerted proton-electron transfer (MS-PCET) and nickel catalysis. The current cross-coupling proceeds with the generation of an alkoxy radical utilizing bond-dissociation free energy (BDFE) as the thermodn. driving force. Subsequently, the resulting remote carbon-centered radicals formed by C-C cleavage merge with the nickel catalytic cycle to create the challenging C(sp3)-C(sp2) bonds.

After consulting a lot of data, we found that this compound(29046-78-4)Reference of Nickel(II) chloride ethylene glycol dimethyl ether complex can be used in many types of reactions. And in most cases, this compound has more advantages.

Reference:
Indole alkaloid derivatives as building blocks of natural products from Bacillus thuringiensis and Bacillus velezensis and their antibacterial and antifungal activity study,
Preparation of Indole Containing Building Blocks for the Regiospecific Construction of Indole Appended Pyrazoles and Pyrroles

Synthetic Route of C4H10Cl2NiO2. The fused heterocycle is formed by combining a benzene ring with a single heterocycle, or two or more single heterocycles. Compound: Nickel(II) chloride ethylene glycol dimethyl ether complex, is researched, Molecular C4H10Cl2NiO2, CAS is 29046-78-4, about Reactions of Late First-Row Transition Metal (Fe-Zn) Dichlorides with a PGeP Pincer Germylene. Author is Arauzo, Ana; Cabeza, Javier A.; Fernandez, Israel; Garcia-Alvarez, Pablo; Garcia-Rubio, Ines; Laglera-Gandara, Carlos J..

The reactivity of the PGeP germylene 2,2′-bis(di-isopropylphosphanylmethyl)-5,5′-dimethyldipyrromethane-1,1′-diylgermanium(II), Ge(pyrmPiPr2)2CMe2, with late first-row transition metal (Fe-Zn) dichlorides has been investigated. All reactions led to PGeP pincer chloridogermyl complexes. The reactions with FeCl2 and CoCl2 afforded paramagnetic square planar complexes of formula [MCl{κ3P,Ge,P-GeCl(pyrmPiPr2)2CMe2}] (M = Fe, Co). While the iron complex maintained an intermediate spin state (S1; μeff = 3.0μB) over the temperature range 50-380 K, the effective magnetic moment of the cobalt complex varied linearly with temperature from 1.9μB at 10 K to 3.6μB at 380 K, indicating a spin crossover behavior that involves S1/2 (predominant at T<180 K) and S3/2 (predominant at T>200 K) species. Both cobalt(II) species were detected by ESR at T<20 K. The reaction of Ge(pyrmPiPr2)2CMe2 with [NiCl2(dme)] (dme = dimethoxyethane) gave a square planar nickel(II) complex, [NiCl{κ3P,Ge,P-GeCl(pyrmPiPr2)2CMe2}], whereas the reaction with CuCl2 involved a redox process that rendered a mixture of the germanium(IV) compound GeCl2(pyrmPiPr2)2CMe2 and a binuclear copper(I) complex, [Cu2{μ-κ3P,Ge,P-GeCl(pyrmPiPr2)2CMe2}2], whose metal atoms are in tetrahedral environments. The reaction of the germylene with ZnCl2 led to the tetrahedral derivative [ZnCl{κ3P,Ge,P-GeCl(pyrmPiPr2)2CMe2}]. Although many compounds look similar to this compound(29046-78-4)Synthetic Route of C4H10Cl2NiO2, numerous studies have shown that this compound(SMILES:COCCOC.Cl[Ni]Cl), has unique advantages. If you want to know more about similar compounds, you can read my other articles.

Reference:
Indole alkaloid derivatives as building blocks of natural products from Bacillus thuringiensis and Bacillus velezensis and their antibacterial and antifungal activity study,
Preparation of Indole Containing Building Blocks for the Regiospecific Construction of Indole Appended Pyrazoles and Pyrroles

Heterocyclic compounds can be divided into two categories: alicyclic heterocycles and aromatic heterocycles. Compounds whose heterocycles in the molecular skeleton cannot reflect aromaticity are called alicyclic heterocyclic compounds. Compound: 29046-78-4, is researched, Molecular C4H10Cl2NiO2, about Generation and Oxidative Reactivity of a Ni(II) Superoxo Complex via Ligand-Based Redox Non-Innocence, the main research direction is hydrazono tolyl pyrrolo nickel complex preparation crystal mol structure; superoxo nickel hydrazono tolyl pyrrolo preparation oxidation alc hydrocarbon.Application of 29046-78-4.

Metal ligand cooperativity is a powerful strategy in transition metal chem. This type of mechanism for the activation of O2 is best exemplified by heme centers in biol. systems. While aerobic oxidations with Fe and Cu are well precedented, Ni-based oxidations are frequently less common due to less-accessible metal-based redox couples. Some Ni enzymes use special ligand environments for tuning the Ni(II)/(III) redox couple such as strongly donating thiolates in Ni superoxide dismutase. A recently characterized example of a Ni-containing protein, however, suggests an alternative strategy for mediating redox chem. with Ni by using ligand-based reducing equivalent to enable O binding. While this mechanism has little synthetic precedent, the authors show here that Ni complexes of the redox-active ligand tBu,TolDHP (tBu,TolDHP = 2,5-bis((2-t-butylhydrazono)(p-tolyl)methyl)-pyrrole) activate O2 to generate a Ni(II) superoxo complex via ligand-based electron transfer. This superoxo complex is competent for stoichiometric oxidation chem. with alcs. and hydrocarbons. Coupling ligand-based redox chem. with functionally redox-inactive Ni centers enables oxidative transformations more commonly mediated by metals such as Fe and Cu.

Although many compounds look similar to this compound(29046-78-4)Application of 29046-78-4, numerous studies have shown that this compound(SMILES:COCCOC.Cl[Ni]Cl), has unique advantages. If you want to know more about similar compounds, you can read my other articles.

Reference:
Indole alkaloid derivatives as building blocks of natural products from Bacillus thuringiensis and Bacillus velezensis and their antibacterial and antifungal activity study,
Preparation of Indole Containing Building Blocks for the Regiospecific Construction of Indole Appended Pyrazoles and Pyrroles

Soegaard, Alexander; de Oliveira, Ana Luiza; Taccardi, Nicola; Haumann, Marco; Wasserscheid, Peter published the article 《Ga-Ni supported catalytically active liquid metal solutions (SCALMS) for selective ethylene oligomerization》. Keywords: ethylene oligomerization silica support gallium nickel catalyst.They researched the compound: Nickel(II) chloride ethylene glycol dimethyl ether complex( cas:29046-78-4 ).Quality Control of Nickel(II) chloride ethylene glycol dimethyl ether complex. Aromatic heterocyclic compounds can be divided into two categories: single heterocyclic and fused heterocyclic. In addition, there is a lot of other information about this compound (cas:29046-78-4) here.

Non-precious metal supported catalytically active liquid metal solutions exhibit attractive performance in ethylene oligomerization. It is found for the Ga-Ni system on silica that the performance depends strongly on the applied Ga/Ni ratio. Ga-rich systems forming liquid alloys exhibit a far higher Ni-based catalytic activity than solid intermetallic compounds or Ni nanoparticles.

After consulting a lot of data, we found that this compound(29046-78-4)Quality Control of Nickel(II) chloride ethylene glycol dimethyl ether complex can be used in many types of reactions. And in most cases, this compound has more advantages.

Reference:
Indole alkaloid derivatives as building blocks of natural products from Bacillus thuringiensis and Bacillus velezensis and their antibacterial and antifungal activity study,
Preparation of Indole Containing Building Blocks for the Regiospecific Construction of Indole Appended Pyrazoles and Pyrroles