Tag: M.W=400-600

Roy, Saswati Ghosh; Mondal, Subhendu; Ghosh, Kumaresh published the artcile< Copillar[5]arene-rhodamine conjugate as a selective sensor for Hg2+ ions>, Quality Control of 950846-89-6, the main research area is copillararene rhodamine conjugate selective sensor mercury.

A new copillar[5]arene coupled rhodamine probe 1 has been designed and synthesized. The mol. probe shows selective sensing of Hg2+ ions over a series of metal ions in CH3CN by exhibiting a color change of the solution as well as ‘turn-on’ fluorescence. Compound 1 also shows interaction with Cu2+ by exhibiting a different color and spectral changes. Furthermore, Hg2+ has been differentiated from Cu2+ by using tetrabutylammonium iodide (TBAI). While in the presence of TBAI, the reddish violet color of the 1-Cu2+ complex becomes colorless with the regeneration of the original electronic spectrum of 1; under identical conditions, the pink color of the 1-Hg2+ complex is not changed in the presence of TBAI. Model compound 2 with no pillar[5]arene moiety has been synthesized to validate the role of pillararene in the selectivity of metal ion sensing. Importantly, compound 2 does not show any selectivity in sensing under identical conditions. Complexation studies are performed by using UV-vis, fluorescence, FTIR and NMR spectroscopic methods.

New Journal of Chemistry published new progress about Colorimetric sensors. 950846-89-6 belongs to class indole-building-block, and the molecular formula is C30H36N4O2, Quality Control of 950846-89-6.

Referemce:
Indole alkaloid derivatives as building blocks of natural products from Bacillus thuringiensis and Bacillus velezensis and their antibacterial and antifungal activity study,
Preparation of Indole Containing Building Blocks for the Regiospecific Construction of Indole Appended Pyrazoles and Pyrroles

Wang, Xiaodong; Fan, Li; Wang, Yubin; Zhang, Caihong; Liang, Wenting; Shuang, Shaomin; Dong, Chuan published the artcile< Visual monitoring of the lysosomal pH changes during autophagy with a red-emission fluorescent probe>, Electric Literature of 950846-89-6, the main research area is lysosome pH autophagy red emission fluorescent probe.

Autophagy plays crucial roles in maintaining normal intracellular homeostasis. Mol. probes capable of monitoring lysosomal pH changes during autophagy are still highly required yet challenging to develop. Here, a lysosome-targeting fluorescent pH probe, RML (I), is presented by introducing a methylcarbitol unit as the lysosome-targeting group to rhodamine B, which is highly sensitive to pH changes. RML exhibits remarkable pH-dependent behavior at 583 nm with a fluorescent enhancement of >148-fold. The pKa value is determined as 4.96, and the linear response with pH changes from 4.50-5.70, which is favorable for lysosomal pH imaging. Also RML diffuses selectively into lysosomes using confocal fluorescence microscopy. Using RML, the authors have successfully visualized autophagy by monitoring the lysosomal pH changes.

Journal of Materials Chemistry B: Materials for Biology and Medicine published new progress about Autophagy. 950846-89-6 belongs to class indole-building-block, and the molecular formula is C30H36N4O2, Electric Literature of 950846-89-6.

Referemce:
Indole alkaloid derivatives as building blocks of natural products from Bacillus thuringiensis and Bacillus velezensis and their antibacterial and antifungal activity study,
Preparation of Indole Containing Building Blocks for the Regiospecific Construction of Indole Appended Pyrazoles and Pyrroles

Tian, Xing-Ling; Feng, Chao; Zhao, Xu-Hui published the artcile< Corrosion Monitoring Effect of Rhodamine-Ethylenediamine on Copper Relics under a Protective Coating>, Safety of 2-(2-Aminoethyl)-3′,6′-bis(diethylamino)spiro[isoindoline-1,9′-xanthen]-3-one, the main research area is rhodamine ethylenediamine copper relics protective coating corrosion.

Fluorescence spectroscopy is a common technique used to monitor early metallic corrosion. The fluorescence response characteristics of rhodamine-ethylenediamine toward Cu2+ have been studied using fluorescence and IR spectroscopy. Fluorescence microscopy and electrochem. impedance spectroscopy were used to study the monitoring effect of rhodamine-ethylenediamine on the corrosion of copper relics protected by an epoxy coating. The results showed a strong fluorescent response and selectivity toward Cu2+ that existed using rhodamine-ethylenediamine. Early metallic corrosion of copper relics can be effectively monitored upon adding 0.8 wt% rhodamine-ethylenediamine to an epoxy coating. When the soaking time was increased, the fluorescence intensity of the fluorescent area on the coating became stronger. In addition, the area of the luminous coating reached ∼0.06 mm2 and the area of corrosion under the protective coating was ∼0.008 mm2, which was about 1/10 of the fluorescence area observed on the coating.

ACS Omega published new progress about Coating process. 950846-89-6 belongs to class indole-building-block, and the molecular formula is C30H36N4O2, Safety of 2-(2-Aminoethyl)-3′,6′-bis(diethylamino)spiro[isoindoline-1,9′-xanthen]-3-one.

Referemce:
Indole alkaloid derivatives as building blocks of natural products from Bacillus thuringiensis and Bacillus velezensis and their antibacterial and antifungal activity study,
Preparation of Indole Containing Building Blocks for the Regiospecific Construction of Indole Appended Pyrazoles and Pyrroles

Banerjee, Sovan Lal; Saha, Pabitra; Ganguly, Ritabrata; Bhattacharya, Koushik; Kalita, Uddhab; Pich, Andrij; Singha, Nikhil K. published the artcile< A dual thermoresponsive and antifouling zwitterionic microgel with pH triggered fluorescent ""on-off"" core>, Application In Synthesis of 950846-89-6, the main research area is thermoresponsive antifouling zwitterionic microgel fluorescence; Antifouling; Dual thermoresponsiveness; Fluorescence; LSCT; Microgel; UCST; Zwitterion.

A unique, tailor-made, zwitterionic, dual thermoresponsive and fluorescent microgel probe was synthesized via Reversible Addition Fragmentation chain-Transfer (RAFT) polymerization Microgels were prepared via oil in water (o/w) emulsion polymerization where poly(carboxybetaine) (PCB) acted as a macro-RAFT reagent as well as an emulsifier. The presence of poly(N-vinylcaprolactam) (PNVCL) in the microgel system imparts the thermoresponsiveness to the system and the presence of a rhodamine derivative as fluorophore makes it responsive to pH change of the system by showing a fluorescence emission at 580 nm (reddish orange color). The dual thermoresponsiveness [i.e. the presence of upper critical solution temperature (UCST @ 12°C) as well as lower critical solution temperature (LCST @ 33°C)] of the microgels was studied via UV-visible spectroscopy (UV-vis) and temperature responsive dynamic light scattering (DLS) analyses. Presence of the PCB in the corona-crosslinked microgel, played a vital role in the formation of self-assembled structure as well as in protein immobilization (antifouling activity). Antifouling property was studied using UV-vis spectroscopy where bovine serum albumin (BSA) was taken as a model protein. The presence of the pH-responsive fluorescence, thermoresponsiveness as well as antifouling properties makes this zwitterionic microgel system a potential a potential candidate for medical diagnostics and for drug delivery vehicles.

Journal of Colloid and Interface Science published new progress about Antifouling agents. 950846-89-6 belongs to class indole-building-block, and the molecular formula is C30H36N4O2, Application In Synthesis of 950846-89-6.

Referemce:
Indole alkaloid derivatives as building blocks of natural products from Bacillus thuringiensis and Bacillus velezensis and their antibacterial and antifungal activity study,
Preparation of Indole Containing Building Blocks for the Regiospecific Construction of Indole Appended Pyrazoles and Pyrroles

Liu, Yuanyuan; Li, Yi; Zong, Linghui; Zhang, Jingyi published the artcile< Comparison of Two Rhodamine-polyamine Polystyrene Solid-phase Fluorescence Sensors for Hg(II) Detection Based on Theoretical Calculation>, Reference of 950846-89-6, the main research area is rhodamine polyamine polystyrene fluorescence sensor mercury detection.

Two novel rhodamine-based polystyrene solid-phase fluorescence sensors PS-PA-I and PS-PA-II with different lengths of polyamines were synthesized for Hg(II) determination The detection mechanism involving the Hg(II) chelation-induced spirocycle open of rhodamine was proposed with the aid of theor. calculation The stronger N-Hg bond and the longer polyamine chain in PS-PA-II led to a better selectivity, much higher and more quickly fluorescence response to Hg(II).

Chemical Research in Chinese Universities published new progress about Fluorescence. 950846-89-6 belongs to class indole-building-block, and the molecular formula is C30H36N4O2, Reference of 950846-89-6.

Referemce:
Indole alkaloid derivatives as building blocks of natural products from Bacillus thuringiensis and Bacillus velezensis and their antibacterial and antifungal activity study,
Preparation of Indole Containing Building Blocks for the Regiospecific Construction of Indole Appended Pyrazoles and Pyrroles

Wu, Guowei; Wang, Zhengyi; Zhang, Weixia; Chen, Wei; Jin, Xinxin; Lu, Hongfei published the artcile< A novel rhodamine B and purine derivative-based fluorescent chemosensor for detection of palladium (II) ion>, SDS of cas: 950846-89-6, the main research area is palladium rhodamine B purine derivative complex formation fluorescent probe; DFT palladium rhodamine B purine derivative; crystal structure rhodamine B purine derivative.

A new rhodamine B and purine-based colorimetric and fluorescent sensor RBTP for detection of Pd (II) cation was prepared and structurally characterized. Sensor RBTP shows high sensitivity and selectivity to Pd2+ in EtOH/H2O solution (3/2, volume/volume, pH 7.4, HEPES buffer, 0.5 mM). And sensor RBTP not only exhibited a naked-eye color change from colorless to pink, but also displayed “”turn-on”” fluorescent sensing for recognition and detection of Pd2+. The fluorescence titration anal. of sensor RBTP to Pd2+ exhibits a low the limit of detection (49.5 nM). A great linear relationship was found between the concentration of Pd2+ from 0 to 40 μM and the fluorescence intensity of RBTP. The crystal structure of RBTP was supported by X-ray diffraction. Meanwhile, the proposed sensing mechanism of RBTP binding to Pd2+ was supported by Job’s plot, MS spectra study and d. functional theory (DFT) study. Moreover, sensor RBTP could be made as test paper to quant. detection for Pd (II) cation in water.

Inorganic Chemistry Communications published new progress about Crystal structure. 950846-89-6 belongs to class indole-building-block, and the molecular formula is C30H36N4O2, SDS of cas: 950846-89-6.

Referemce:
Indole alkaloid derivatives as building blocks of natural products from Bacillus thuringiensis and Bacillus velezensis and their antibacterial and antifungal activity study,
Preparation of Indole Containing Building Blocks for the Regiospecific Construction of Indole Appended Pyrazoles and Pyrroles

Cengiz, Nergiz published the artcile< Fabrication of Multifunctional Stimuli-Responsive Hydrogels Susceptible to both pH and Metal Cation for Visual Detections>, Quality Control of 950846-89-6, the main research area is multifunctional stimuli responsive hydrogel pH metal cation colorimetric sensor.

Advances in several areas of contemporary biomaterial science are closely related to the design of stimuli-responsive smart materials. An important aspect that governs widespread adaptation of a synthetic biomaterial depends on its ease of synthesis, as well as facile functionalization. Readily available homo-bifunctional PEG-based diamines are mixed with a tetra-arm epoxide based cross-linker to yield hydrogels through the epoxy-amine addition reaction. Hydrogels obtained with varying chain lengths of PEG polymer were characterized for their morphol., swelling, and rheol. properties. The residual epoxide groups within the hydrogel were used for post-gelation functionalization to obtain a functional material. In particular, functionalization with an amine-containing rhodamine derivative yields a hydrogel that serves as a colorimetric sensor for acidic pH environment, and indicates Fe3+ cation with high specificity.

Macromolecular Chemistry and Physics published new progress about Cations. 950846-89-6 belongs to class indole-building-block, and the molecular formula is C30H36N4O2, Quality Control of 950846-89-6.

Referemce:
Indole alkaloid derivatives as building blocks of natural products from Bacillus thuringiensis and Bacillus velezensis and their antibacterial and antifungal activity study,
Preparation of Indole Containing Building Blocks for the Regiospecific Construction of Indole Appended Pyrazoles and Pyrroles

Cheng, Zhiyang; Qin, Qingwen; Jia, Hui; Li, Juan; Yan, Fanyong; Meng, Xia; Wang, Jie published the artcile< Scale evaluation and antiscalant testing based on fluorescent probe technology in RO process>, COA of Formula: C30H36N4O2, the main research area is aminotrimethylene phosphonic acid fluorescent probe reverse osmosis.

Inventing the technol. based on fluorescent probes to detect antiscalants in reverse osmosis (RO) concentrated water is of great significance for guiding the use of antiscalant and the control of scale. In this study, Amino trimethylene phosphonic acid (ATMP) was taken as the representative of the antiscalant, and a new fluorescent probe for ATMP detection was designed and synthesized. The new fluorescent probe showed high accuracy for ATMP detection (R2 > 0.94) and resistance to the interference of ions (change rate <3%). Further, the use of probe to detect the antiscalant in RO concentrate and realize the evaluation of the scaling phenomenon was carried out. The model of the relationship between the probe fluorescence intensity and the concentration of precipitated ions was established to analyze the scale evaluation mechanism of the probe. Meanwhile, Critical fluorescence intensity (CFI) was introduced for scale evaluation. The results showed that the new probe could accurately judge the formation of scale under the condition of different antiscalant concentrations, and 926 ± 20 a.u. was judged as CFI for scaling evaluation. Finally, results of the new probe detection in RO scale evaluation test were consistent with the membrane flux and SEM detection, indicating that the probe can accurately evaluate scale during the RO operation. This research can provide tech. support for the precise application of antiscalants and scale inhibition. Journal of Membrane Sciencepublished new progress about Electric conductivity. 950846-89-6 belongs to class indole-building-block, and the molecular formula is C30H36N4O2, COA of Formula: C30H36N4O2.

Referemce:
Indole alkaloid derivatives as building blocks of natural products from Bacillus thuringiensis and Bacillus velezensis and their antibacterial and antifungal activity study,
Preparation of Indole Containing Building Blocks for the Regiospecific Construction of Indole Appended Pyrazoles and Pyrroles

Tian, Xing-Ling; Feng, Chao; Zhao, Xu-Hui team published the artcile< Corrosion Monitoring Effect of Rhodamine-Ethylenediamine on Copper Relics under a Protective Coating>, the main research area is rhodamine ethylenediamine copper relics protective coating corrosion. COA of Formula: C30H36N4O2.

Fluorescence spectroscopy is a common technique used to monitor early metallic corrosion. The fluorescence response characteristics of rhodamine-ethylenediamine toward Cu2+ have been studied using fluorescence and IR spectroscopy. Fluorescence microscopy and electrochem. impedance spectroscopy were used to study the monitoring effect of rhodamine-ethylenediamine on the corrosion of copper relics protected by an epoxy coating. The results showed a strong fluorescent response and selectivity toward Cu2+ that existed using rhodamine-ethylenediamine. Early metallic corrosion of copper relics can be effectively monitored upon adding 0.8 wt% rhodamine-ethylenediamine to an epoxy coating. When the soaking time was increased, the fluorescence intensity of the fluorescent area on the coating became stronger. In addition, the area of the luminous coating reached ∼0.06 mm2 and the area of corrosion under the protective coating was ∼0.008 mm2, which was about 1/10 of the fluorescence area observed on the coating.

ACS Omegapublished new progress about Coating process; Complexation; Corrosion (relics); Electric impedance; Fluorescence spectroscopy; Fluorescent coating materials; Surface structure. 950846-89-6 belongs to class indole-building-block and the molecular formula is C30H36N4O2, Indole alkaloid derivatives as building blocks of natural products from Bacillus thuringiensis and Bacillus velezensis and their antibacterial and antifungal activity study.

Referemce:
Indole alkaloid derivatives as building blocks of natural products from Bacillus thuringiensis and Bacillus velezensis and their antibacterial and antifungal activity study,
Preparation of Indole Containing Building Blocks for the Regiospecific Construction of Indole Appended Pyrazoles and Pyrroles