Indole, first isolated in 1866, has the molecular formula C8H7N, and it is commonly synthesized from phenylhydrazine and pyruvic acid, 19005-93-7, formula is C9H7NO, Name is 1H-Indole-2-carbaldehyde. although several other procedures have been discovered.Indole is a colourless solid having a pleasant fragrance in highly dilute solutions. It melts at 52.5° C (126.5° F). Synthetic Route of 19005-93-7.
Taneda, Masatsugu;Nishi, Masato;Kubono, Koji;Kashiwagi, Yukiyasu;Matsumoto, Taisuke research published 《 Crystal structure of N-(1H-indol-2-ylmethylidene)-4-methoxyaniline》, the research content is summarized as follows. The mol. of the title compound, C16H14N2O, contains an essentially planar indole ring system and a Ph ring. In the crystal, the mols. are linked by a weak intermol. C-H···O hydrogen bond and C-H···π interactions, forming a one-dimensional column structure along the b-axis direction. These columns are linked by other C-H···πinteractions, forming a two-dimensional network structure.
Synthetic Route of 19005-93-7, 1H-Indole-2-carbaldehyde is a useful research compound. Its molecular formula is C9H7NO and its molecular weight is 145.16 g/mol. The purity is usually 95%.
1H-Indole-2-carbaldehyde is a useful research chemical used as a reactant in the synthesis of substituted 2-amino-4H-chromenes and benzochromenes using K2CO3 as catalyst.
1H-Indole-2-carbaldehyde is a solvent that has been used in the protein data and molecular modeling study. The 1H NMR spectrum of this compound showed an intense signal at δ 4.8 ppm, corresponding to the hydroxyl proton. This solvent also has fluorescence properties, as shown by its photophysical and structural analysis. The 1H-indole-2-carbaldehyde molecule has an active methylene group and an oxindole ring with amine substituents., 19005-93-7.
Referemce:
Indole alkaloid derivatives as building blocks of natural products from Bacillus thuringiensis and Bacillus velezensis and their antibacterial and antifungal activity study,
Preparation of Indole Containing Building Blocks for the Regiospecific Construction of Indole Appended Pyrazoles and Pyrroles