Tani, Masanobu published the artcileNew strategy for indole synthesis from ethyl pyrrole-2-carboxylate (synthetic studies on indoles and related compounds. XXXIX), COA of Formula: C12H13NO3, the publication is Chemical & Pharmaceutical Bulletin (1996), 44(1), 55-61, database is CAplus.
As a synthetic application of the previously reported C4-acylation of Et pyrrole-2-carboxylate, a new strategy for indole synthesis was developed. Et pyrrole-2-carboxylate was allowed to react with succinic anhydride or 3-methoxycarbonylpropionyl chloride to give, in good yield, a C4-succinyl derivative, which was converted into Et 7-oxo-4,5,6,7-tetrahydroindole-2-carboxylate (I) as a key intermediate for indole synthesis. Starting from I, several indoles functionalized on the benzene moiety were synthesized.
Chemical & Pharmaceutical Bulletin published new progress about 20538-12-9. 20538-12-9 belongs to indole-building-block, auxiliary class Indole,Ester,Ether, name is Ethyl 7-methoxy-1H-indole-2-carboxylate, and the molecular formula is C9H10O4, COA of Formula: C12H13NO3.
Referemce:
https://www.nature.com/articles/s41429-020-0333-2,
Preparation of Indole Containing Building Blocks for the Regiospecific Construction of Indole Appended Pyrazoles and Pyrroles