Synthetic Route of 1953-54-4, The transformation of simple hydrocarbons into more complex and valuable products via catalytic C–H bond functionalisation has revolutionised modern synthetic chemistry. 1953-54-4, Name is 5-Hydroxyindole, SMILES is C1=CC2=C([NH]1)C=CC(=C2)O, belongs to indole-building-block compound. In a article, author is Rassi, Somayeh, introduce new discover of the category.
A green and efficient one pot procedure to achieve indole based amides using Passerini reaction involving indole-2-carboxylic acids, aromatic aldehydes and alkyl isocyanides in the presence of immobilized lipase on graphene oxide as a heterogeneous nano biocatalyst has been developed. This method has the advantages of simple operation, mild reaction conditions and good to excellent yields. The features of this method are highlighted by using a retrievable nanostructure catalyst. This process has asserted to he efficient in the synthesis of indole derivatives. (C) 2019 Elsevier Ltd. All rights reserved.
Synthetic Route of 1953-54-4, Each elementary reaction can be described in terms of its molecularity, the number of molecules that collide in that step. The slowest step in a reaction mechanism is the rate-determining step.you can also check out more blogs about 1953-54-4.
Reference:
Indole alkaloid derivatives as building blocks of natural products from Bacillus thuringiensis and Bacillus velezensis and their antibacterial and antifungal activity study,
,Preparation of Indole Containing Building Blocks for the Regiospecific Construction of Indole Appended Pyrazoles and Pyrroles