Electric Literature of 20559-55-1, The transformation of simple hydrocarbons into more complex and valuable products via catalytic C–H bond functionalisation has revolutionised modern synthetic chemistry. 20559-55-1, Name is Oxibendazole, SMILES is O=C(OC)NC1=NC2=CC(OCCC)=CC=C2N1, belongs to indole-building-block compound. In a article, author is Zhang, Tao, introduce new discover of the category.
Palladium-Catalyzed Tandem Carbocyclization and Hetroarylation for the Synthesis of 2-(Trifluoromethyl)indenylmethyleneindoles
A palladium-catalyzed tandem cyclization and cross-coupling reaction of o-(2-chlorovinyl)alkynylbenzenes with indoles/pyrroles is developed. The process proceeds via intramolecular carbocyclization and subsequent hetroarylation to afford previously unknown trifluoromethyl-containing indenylmethyleneindoles, which are potentially useful in drug design.
Electric Literature of 20559-55-1, One of the oldest and most widely used commercial enzyme inhibitors is aspirin, which selectively inhibits one of the enzymes involved in the synthesis of molecules that trigger inflammation. you can also check out more blogs about 20559-55-1.
Reference:
Indole alkaloid derivatives as building blocks of natural products from Bacillus thuringiensis and Bacillus velezensis and their antibacterial and antifungal activity study,
,Preparation of Indole Containing Building Blocks for the Regiospecific Construction of Indole Appended Pyrazoles and Pyrroles