An article Comparing the predictability of different chemometric models over UV-spectral data of isoxsuprine and its toxic photothermal degradation products WOS:000472094000053 published article about MULTIVARIATE CALIBRATION METHODS; HYDROCHLORIDE in [Saad, Ahmed S.; Elzanfaly, Eman S.; Kelani, Khadiga M.] Cairo Univ, Fac Pharm, Analyt Chem Dept, El Kasr El Aini St, ET-11562 Cairo, Egypt; [Saad, Ahmed S.; Halim, Michael K.] October 6 Univ, Fac Pharm, Chem Dept, 6 October City 12585, Egypt; [Kelani, Khadiga M.] Modern Technol & Informat Univ, Analyt Chem Dept, Fac Pharm, Cairo, Egypt in 2019.0, Cited 27.0. The Name is 4′-Hydroxyacetophenone. Through research, I have a further understanding and discovery of 99-93-4. Safety of 4′-Hydroxyacetophenone
Isoxsuprine (ISX) is widely used for cerebral and peripheral vascular diseases. A comparative study was held among different multivariate calibration models for selective determination of a complex mixture of Isoxsuprine and four of its toxic photothermal degradation products that impair kidney and liver functions. The Partial Least Squares (PLS) and Artificial Neural Network (ANN) models were applied on the specific spectrum and on selected wavelengths using genetic algorithm (GA) technique as an efficient variable selection tool. The effect of GA on the model construction and performance was evaluated. The multilevel multifactor experimental design was adopted for the construction of the calibration set. Optimized parameters were used for the development of the different models. The performances of the developed models were assessed by predicting the concentration of eight different mixtures composing the validation set. Results were compared to one another and to the official method using one-way ANOVA statistical test to assure the validity of the constructed models. The lower chance of overfitting offered by ANN minimized the RMS EP relative to the PIS. On the other hand, the application of GA prior to model implementation affected the number of latent variables the prediction ability of both PIS and ANN models. The validated models were successfully applied as stability indicating assay methods for the selective determination of ISX and its photothermal degradation products in ISX raw material and market formulations. (C) 2019 Elsevier B.V. All rights reserved.
Safety of 4′-Hydroxyacetophenone. Welcome to talk about 99-93-4, If you have any questions, you can contact Saad, AS; Elzanfaly, ES; Halim, MK; Kelani, KM or send Email.
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Indole alkaloid derivatives as building blocks of natural products from Bacillus thuringiensis and Bacillus velezensis and their antibacterial and antifungal activity study,
,Preparation of Indole Containing Building Blocks for the Regiospecific Construction of Indole Appended Pyrazoles and Pyrroles