Related Products of 52415-29-9, The reaction rate of a catalyzed reaction is faster than the reaction rate of the uncatalyzed reaction at the same temperature.52415-29-9, Name is 6-Bromoindole, molecular formula is C8H6BrN. In a Article，once mentioned of 52415-29-9
A novel Friedel-Crafts reaction of indoles with vicinal tricarbonyl compounds generated in situ from 1,3-dicarbonyl compounds, which produces indole substituted tertiary alcohols in good to excellent yields and with good functional group tolerance, has been developed. The mechanistic pathway for this process involves the initial disproportionation of TEMPO, alpha-oxyamination of the 1,3-dicarbonyl compound followed by N-O bond cleavage to form the tricarbonyl intermediate. Addition of indole to this intermediate then generates the tertiary alcohol product. This method can also be used for the synthesis of pyrrole-containing tertiary alcohols. Further efforts aimed at elucidating the mechanism of the reaction and boardening the substrate scope of this process are ongoing.
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Reference：
Indole alkaloid derivatives as building blocks of natural products from Bacillus thuringiensis and Bacillus velezensis and their antibacterial and antifungal activity study,
Preparation of Indole Containing Building Blocks for the Regiospecific Construction of Indole Appended Pyrazoles and Pyrroles