Application In Synthesis of Bis((S)-4-phenyl-4,5-dihydrooxazol-2-yl)methane. The mechanism of aromatic electrophilic substitution of aromatic heterocycles is consistent with that of benzene. Compound: Bis((S)-4-phenyl-4,5-dihydrooxazol-2-yl)methane, is researched, Molecular C19H18N2O2, CAS is 132098-59-0, about Scope and limitations of chiral bis(oxazoline) ligands in the copper-catalysed asymmetric cyclopropanation of trisubstituted alkenes. Author is Ostergaard, N.; Jensen, J. F.; Tanner, D..
A series of derivatives of 3-methyl-2-buten-1-ol, Me2C:CHCH2OR (R = Ac, PhCH2, 4-O2NC6H4CO, etc.), has been used to test the scope and limitations of the copper-catalyzed asym. cyclopropanation of trisubstituted alkenes by Et diazoacetate in the presence of C2-sym. bis(oxazoline) ligands. In the best case, a trans/cis ratio of 91:9, with 92% ee for the major isomer, was obtained from the reaction of the p-methoxybenzoate derivative The highest ee was 95%, for the trans isomer of a 80:20 diastereomer mixture (acetate derivative).
In addition to the literature in the link below, there is a lot of literature about this compound(Bis((S)-4-phenyl-4,5-dihydrooxazol-2-yl)methane)Application In Synthesis of Bis((S)-4-phenyl-4,5-dihydrooxazol-2-yl)methane, illustrating the importance and wide applicability of this compound(132098-59-0).
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Indole alkaloid derivatives as building blocks of natural products from Bacillus thuringiensis and Bacillus velezensis and their antibacterial and antifungal activity study,
Preparation of Indole Containing Building Blocks for the Regiospecific Construction of Indole Appended Pyrazoles and Pyrroles