Application of 854778-47-5, Chemistry is the experimental science by definition. We want to make observations to prove hypothesis. For this purpose, we perform experiments in the lab. 854778-47-5, Name is 1-Ethyl-1H-indole-6-carbaldehyde,introducing its new discovery.
The invention relates to the field of pharmacochemistry and pharmacotherapeutics and particularly relates to a tricyclic indole compound (I) with PARP (Poly-ADP-Ribose Polymerase) inhibiting activity, a preparation method and an application thereof. The R1 and R2 are defined as the specification. Proved by pharmacodynamic test, the tricyclic indole compound has the PARP inhibiting action and can be used for adjuvant therapy of tumor diseases. (img file=’DDA0000460768850000011. TIF’wi =’512′ he=’494’/).
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Reference：
Indole alkaloid derivatives as building blocks of natural products from Bacillus thuringiensis and Bacillus velezensis and their antibacterial and antifungal activity study,
Preparation of Indole Containing Building Blocks for the Regiospecific Construction of Indole Appended Pyrazoles and Pyrroles