HPLC of Formula: 2208-59-5. The reaction of aromatic heterocyclic molecules with protons is called protonation. Aromatic heterocycles are more basic than benzene due to the participation of heteroatoms. Compound: 2-(Pyridin-4-yl)-1H-benzo[d]imidazole, is researched, Molecular C12H9N3, CAS is 2208-59-5, about Prototropic equilibria of 2-pyridylbenzimidazoles in aqueous solution. Author is Novo, Mercedes; Mosquera, Manuel; Rodriguez Prieto, Flor.
The acid-base behavior of 2-(n’-pyridyl)benzimidazoles (n’ = 2,3,4) and some Me derivatives was studied in aqueous solution over a wide range of acidity; interesting features with respect to competition in protonation between the benzimidazole N3 and the pyridyl N were observed along with the existence of the corresponding 2 monocations in equilibrium in the case of n’ = 4. The influence of pH on the electronic absorption spectra of all these compounds was studied to identify the ground-state species present as a function of acidity and to obtain the acidity constants of the various prototropic equilibrium occurring in the wide range of acidity studied.
The article 《Prototropic equilibria of 2-pyridylbenzimidazoles in aqueous solution》 also mentions many details about this compound(2208-59-5)HPLC of Formula: 2208-59-5, you can pay attention to it, because details determine success or failure
Reference:
Indole alkaloid derivatives as building blocks of natural products from Bacillus thuringiensis and Bacillus velezensis and their antibacterial and antifungal activity study,
Preparation of Indole Containing Building Blocks for the Regiospecific Construction of Indole Appended Pyrazoles and Pyrroles