The preparation of ester heterocycles mostly uses heteroatoms as nucleophilic sites, which are achieved by intramolecular substitution or addition reactions. Compound: Nickel(II) chloride ethylene glycol dimethyl ether complex( cas:29046-78-4 ) is researched.Recommanded Product: 29046-78-4.Zhang, Shou-Kun; Struwe, Julia; Hu, Lianrui; Ackermann, Lutz published the article 《Nickela-electrocatalyzed C-H Alkoxylation with Secondary Alcohols: Oxidation-Induced Reductive Elimination at Nickel(III)》 about this compound( cas:29046-78-4 ) in Angewandte Chemie, International Edition. Keywords: benzamide secondary alc nickel electrocatalyst alkoxylation DFT directing group; C−H alkoxylation; electrocatalysis; electrochemistry; nickel; oxygenation. Let’s learn more about this compound (cas:29046-78-4).
Nickela-electrooxidative C-H alkoxylations with challenging secondary alcs. were accomplished in a fully dehydrogenative fashion, thereby avoiding stoichiometric chem. oxidants, with H2 as the only stoichiometric byproduct. The nickel-electrocatalyzed oxygenation proved viable with various (hetero)arenes, including naturally occurring secondary alcs., without racemization. Detailed mechanistic investigation, including DFT calculations and cyclovoltammetric studies of a well-defined C-H activated nickel(III) intermediate, suggest an oxidation-induced reductive elimination at nickel(III).
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Indole alkaloid derivatives as building blocks of natural products from Bacillus thuringiensis and Bacillus velezensis and their antibacterial and antifungal activity study,
Preparation of Indole Containing Building Blocks for the Regiospecific Construction of Indole Appended Pyrazoles and Pyrroles