The three-dimensional configuration of the ester heterocycle is basically the same as that of the carbocycle. Compound: 2-Phenylpyridine(SMILESS: C1(C2=CC=CC=C2)=NC=CC=C1,cas:1008-89-5) is researched.COA of Formula: C12H12N2. The article 《Borane-Catalyzed Chemoselective and Enantioselective Reduction of 2-Vinyl-Substituted Pyridines》 in relation to this compound, is published in Angewandte Chemie, International Edition. Let’s take a look at the latest research on this compound (cas:1008-89-5).
Herein, we report that highly chemoselective and enantioselective reduction of 2-vinyl-substituted pyridines has been achieved for the first time. The reaction, which uses chiral spiro-bicyclic bisboranes as catalysts and HBpin and an acidic amide as reducing reagents, proceeds through a cascade process involving 1,4-hydroboration followed by transfer hydrogenation of a dihydropyridine intermediate. The retained double bond in the reduction products permits their conversion to natural products and other useful heterocyclic compounds by simple transformations.
Compound(1008-89-5)Formula: C11H9N received a lot of attention, and I have introduced some compounds in other articles, similar to this compound(2-Phenylpyridine), if you are interested, you can check out my other related articles.
Reference:
Indole alkaloid derivatives as building blocks of natural products from Bacillus thuringiensis and Bacillus velezensis and their antibacterial and antifungal activity study,
Preparation of Indole Containing Building Blocks for the Regiospecific Construction of Indole Appended Pyrazoles and Pyrroles