Recently I am researching about QUINIC ACID-ESTERS; PHENYLETHANOID GLYCOSIDES; CUCURBITACIN GLYCOSIDES; TRITERPENE GLYCOSIDES; MEDICINAL FOODSTUFFS; BITTER PRINCIPLE; NATURAL-PRODUCTS; PICROSIDE-I; PICROLIV; OLIGOGLYCOSIDES, Saw an article supported by the JSPS KAKENHI, JapanMinistry of Education, Culture, Sports, Science and Technology, Japan (MEXT)Japan Society for the Promotion of ScienceGrants-in-Aid for Scientific Research (KAKENHI) [18K06726, 18K06739]. Published in ELSEVIER in AMSTERDAM ,Authors: Morikawa, T; Inoue, N; Nakanishi, Y; Manse, Y; Matsuura, H; Okino, K; Hamasaki, S; Yoshikawa, M; Muraoka, O; Ninomiya, K. The CAS is 99-93-4. Through research, I have a further understanding and discovery of 4′-Hydroxyacetophenone. SDS of cas: 99-93-4
Three new acylated phenylethanoid glycosides, kurroaosides A (14), B (15), and C (16), and a new acylated cucurbitane-type triterpene glycoside, kurroaoside D (17), were isolated from a methanol extract of the rhizomes of Picrorhiza kurroa Royle ex Benth. (Plantaginaceae) along with 29 known isolates including 10 acylated phenylethanoid glycosides (18-27), three cucurbitane-type triterpene glycosides (32-34), and a nortriterpene glycoside (35). The structures of these new compounds (14-17), including their stereochemistry, were determined based on chemical and physicochemical evidence derived from NMR and MS analysis. Among the isolates, acylated iridoid glycosides, picrosides I (8), 11 (9), III (10), and IV (11) and 6-feruloylcatalpol (12), phenylethanoid glycosides (14-16), triterpene glycosides, cucurbitacin B 2-O-beta-D-glucopyranoside (32) and 25-acetoxy-2-beta-D glucopyranosyloxy 3,16,20-trihydroxy-9-methyl-19 norlanosta-5-en-22 one (35), and an acetophenone glycoside, picein (36), significantly promoted collagen synthesis at 10-30 mu M, with no cytotoxicity being observed at the effective concentrations. Furthermore, acylated phenylethanoid glycosides, calceolarioside A (19, IC50 = 69.2 mu M), plantamajoside (20, 51.8 mu M), isoplantamajoside (21, 76.8 mu M), and scroside E (23, 65.5 mu M), exhibited collagenase inhibitory activity equivalent to that of positive agents caffeic acid (75.6 mu M) and epigallocatechin 3-O-gallate (75.4 mu M).
Welcome to talk about 99-93-4, If you have any questions, you can contact Morikawa, T; Inoue, N; Nakanishi, Y; Manse, Y; Matsuura, H; Okino, K; Hamasaki, S; Yoshikawa, M; Muraoka, O; Ninomiya, K or send Email.. SDS of cas: 99-93-4
Reference:
Indole alkaloid derivatives as building blocks of natural products from Bacillus thuringiensis and Bacillus velezensis and their antibacterial and antifungal activity study,
,Preparation of Indole Containing Building Blocks for the Regiospecific Construction of Indole Appended Pyrazoles and Pyrroles