On May 1, 2020, Thombal, Raju S.; Lee, Yong Rok published an article.COA of Formula: C11H11NO2 The title of the article was Palladium-Catalyzed Direct Oxidative C-H Activation/Annulation for Regioselective Construction of N-Acylindoles. And the article contained the following:
A Pd(II)-catalyzed C(sp3)-H/C(sp2)-H coupling/annulation of anilides and α-dicarbonyl compounds for the synthesis of diverse N-acyl indoles was described. The reaction was achieved by cascade C-H activation, coupling, and intramol. cyclization. This protocol provided a variety of indoles with high functional group tolerance and excellent regioselectivity. The utility of this protocol was demonstrated by transforming the synthesized compound into diversely functionalized analogs. The experimental process involved the reaction of Methyl 2-methyl-1H-indole-3-carboxylate(cas: 65417-22-3).COA of Formula: C11H11NO2
The Article related to acylindole regioselective preparation, anilide dicarbonyl compound coupling intramol cyclizn, Heterocyclic Compounds (One Hetero Atom): Indoles, Indolizines, Carbazoles, and Other Arenopyrroles and other aspects.COA of Formula: C11H11NO2
Referemce:
Indole alkaloid derivatives as building blocks of natural products from Bacillus thuringiensis and Bacillus velezensis and their antibacterial and antifungal activity study,
Preparation of Indole Containing Building Blocks for the Regiospecific Construction of Indole Appended Pyrazoles and Pyrroles