Tobrman, Tomas published the artcileAluminum chloride promoted cross-coupling of trisubstituted enol phosphates with organozinc reagents en route to stereoselective synthesis of tamoxifen and its analogues, Product Details of C15H14BNO4S, the publication is European Journal of Organic Chemistry (2016), 2016(29), 5037-5044, database is CAplus.
In the presence of Pd(S-Phos)2Cl2 [S-Phos = (2′,6′-dimethoxy-1,1-biphenyl-2-yl)dicyclohexylphosphine], aluminum chloride acts as a promoter for the diastereoselective Negishi coupling reactions of arylzinc chlorides or tribenzylaluminum (generated in situ) with enol phosphates to yield aryl alkenes with high stereoselectivities; using dibromoalkenyl phosphates, tri- and tetraaryl alkenes were prepared stereoselectively. Using this method, tamoxifen and two analogs were prepared stereoselectively in >98:2 diastereoselectivities.
European Journal of Organic Chemistry published new progress about 149108-61-2. 149108-61-2 belongs to indole-building-block, auxiliary class Indole,Boronic acid and ester,Sulfamide,Benzene,Boronic Acids,Boronic Acids,Boronic acid and ester,, name is (1-tosyl-1H-Indol-3-yl)boronic acid, and the molecular formula is C10H15NO, Product Details of C15H14BNO4S.
Referemce:
https://www.nature.com/articles/s41429-020-0333-2,
Preparation of Indole Containing Building Blocks for the Regiospecific Construction of Indole Appended Pyrazoles and Pyrroles