Synthetic Route of 3846-71-7, The transformation of simple hydrocarbons into more complex and valuable products via catalytic C–H bond functionalisation has revolutionised modern synthetic chemistry. 3846-71-7, Name is 2-(2H-Benzo[d][1,2,3]triazol-2-yl)-4,6-di-tert-butylphenol, SMILES is OC1=C(C(C)(C)C)C=C(C(C)(C)C)C=C1N2N=C(C=CC=C3)C3=N2, belongs to indole-building-block compound. In a article, author is Raju, Koppada Masthan, introduce new discover of the category.
A simple, efficient, and cheap strategy has been developed for N-arylation of indoles with hexafloro benzene (1) via incorporating sulfolane as an eco-friendly solvent. N-Monopentafluoroarylindole (3) at ambient conditions and N, N-bistetrafluomaryl indole (4) at elevated temperatures were conveniently obtained by simple nucleophilic substitution using NaOH as the base and sulfolane as a reaction medium to obtain in moderately good yields, respectively. Subsequently, 3-chloro, 3-bromo, and 3-iodomono-pentafluoroarylindoles and 3, 3′-dichloro, 3, 3′-dibromo and 3, 3′-dilodobistetrafluoroaryl indoles were prepared in good yields by using respective halogenating reagents and solvents. All the chemical transformations were confirmed by analytical tools such as 1HNMR, FR-IR and HRMS analysis.
Synthetic Route of 3846-71-7, The reactant in an enzyme-catalyzed reaction is called a substrate. Enzyme inhibitors cause a decrease in the reaction rate of an enzyme-catalyzed reaction.I hope my blog about 3846-71-7 is helpful to your research.
Reference:
Indole alkaloid derivatives as building blocks of natural products from Bacillus thuringiensis and Bacillus velezensis and their antibacterial and antifungal activity study,
,Preparation of Indole Containing Building Blocks for the Regiospecific Construction of Indole Appended Pyrazoles and Pyrroles