In an article, author is Chen, Lingjuan, once mentioned the application of 167869-21-8, Safety of PD98059, Name is PD98059, molecular formula is C16H13NO3, molecular weight is 267.28, MDL number is MFCD00671789, category is indole-building-block. Now introduce a scientific discovery about this category.
Cu-catalysed direct bis-thiolation of benzoheterocycles with arylsulfonyl hydrazides
A series of bis-arylsulfenylated indoles (10), benzofurans (3), and benzothiophenes (3) and of monosulfenylated indoles (5), 12 of which are novel, were prepared in good yields via a Cu-catalysed direct sulfenylation of benzoheterocycles with arylsulfonyl hydrazides. Sulfonothioates are probably the major thiolated intermediates in this transformation.
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Reference:
Indole alkaloid derivatives as building blocks of natural products from?Bacillus thuringiensis?and?Bacillus velezensis?and their antibacterial and antifungal activity study,
,Preparation of Indole Containing Building Blocks for the Regiospecific Construction of Indole Appended Pyrazoles and Pyrroles