Synthetic Route of 5355-16-8, Catalysts allow a reaction to proceed via a pathway that has a lower activation energy than the uncatalyzed reaction. 5355-16-8, Name is Diaveridine, SMILES is NC1=NC=C(CC2=CC=C(OC)C(OC)=C2)C(N)=N1, belongs to indole-building-block compound. In a article, author is He, Jiaming, introduce new discover of the category.
Palladium-Catalyzed C-N Bond Formation: A Straightforward Alkoxymethylation Process for the Synthesis of the C1 and C3-Dialkoxy Indoles
A novel approach for the synthesis of the C1 and C3-dialkoxy indoles has been developed for using 2-(phenylethynyl)aniline with formaldehyde and alcohols under the catalysis of acid and palladium acetate. This multicomponent reaction that provides a straightforward alkoxymethylation process to construct substituted indoles is expected to be an important method for the synthesis of indole derivatives.
Synthetic Route of 5355-16-8, Because enzymes can increase reaction rates by enormous factors and tend to be very specific, typically producing only a single product in quantitative yield, they are the focus of active research.you can also check out more blogs about 5355-16-8.
Reference:
Indole alkaloid derivatives as building blocks of natural products from?Bacillus thuringiensis?and?Bacillus velezensis?and their antibacterial and antifungal activity study,
,Preparation of Indole Containing Building Blocks for the Regiospecific Construction of Indole Appended Pyrazoles and Pyrroles