Uno, Tetsuo’s team published research in Tetrahedron Letters in 40 | CAS: 167015-84-1

Tetrahedron Letters published new progress about 167015-84-1. 167015-84-1 belongs to indole-building-block, auxiliary class Indols, name is tert-Butyl 3-(2-aminoethyl)-1H-indole-1-carboxylate, and the molecular formula is C7H16Cl2Si, Application of tert-Butyl 3-(2-aminoethyl)-1H-indole-1-carboxylate.

Uno, Tetsuo published the artcileNew submonomers for poly N-substituted glycines (peptoids), Application of tert-Butyl 3-(2-aminoethyl)-1H-indole-1-carboxylate, the publication is Tetrahedron Letters (1999), 40(8), 1475-1478, database is CAplus.

Five protected submonomers for peptoid synthesis were prepared, i.e., Nin-BOC-tryptamine, O-t-butyltyramine, PMC-guanidino-propylamine, 6-amino-6-deoxy-D-galactopyranose diacetonide, and 5-amino-2,2-dimethyl-1,3-dioxane. The first three mimic natural amino acid side chains, i.e., tryptophan, tyrosine, and arginine, while the last two provide hydrophilic side chains. These submonomers were successfully used for preparation of oligo-peptoids by the submonomer synthesis method.

Tetrahedron Letters published new progress about 167015-84-1. 167015-84-1 belongs to indole-building-block, auxiliary class Indols, name is tert-Butyl 3-(2-aminoethyl)-1H-indole-1-carboxylate, and the molecular formula is C7H16Cl2Si, Application of tert-Butyl 3-(2-aminoethyl)-1H-indole-1-carboxylate.

Referemce:
https://www.nature.com/articles/s41429-020-0333-2,
Preparation of Indole Containing Building Blocks for the Regiospecific Construction of Indole Appended Pyrazoles and Pyrroles