Wang, Kun-Peng; Zheng, Wen-Jun; Lei, Yang; Zhang, Si-Jie; Zhang, Qi; Chen, Shaojin; Hu, Zhi-Qiang published the artcile< A thiophene-rhodamine dyad as fluorescence probe for ferric ion and its application in living cells imaging>, Category: indole-building-block, the main research area is thiophene rhodamine dyad fluorescence probe ferric ion cell imaging.
A thiophene-rhodamine dyad (BYY) was easily synthesized as a fluorescence probe from 2-thiopheneacetic acid and N-(rhodamine-B)lactam-ethylenediamine. The probe showed high response speed and sensitivity toward Fe3+ in ethanol/water (2/3, volume/volume, pH = 7.2), and the limit of detection was as low as 10-7 M. From the Job’s plot, mass spectrum, 1H NMR spectra and the theor. calculation, the 1:2 complex ratio of Fe3+-probe was obtained and the response mechanism was determined Significantly, the reversible binding of BYY to Fe3+ was achieved through the strong Fe3+ affinity of Na4P2O7, and the probe showed well antijamming abilities in the presence of common metal ions. Moreover, the probe was cell-permeable and could sensitively response to Fe3+ in living cells with satisfying resolution
Journal of Luminescence published new progress about Fluorescence. 950846-89-6 belongs to class indole-building-block, and the molecular formula is C30H36N4O2, Category: indole-building-block.
Referemce:
Indole alkaloid derivatives as building blocks of natural products from Bacillus thuringiensis and Bacillus velezensis and their antibacterial and antifungal activity study,
Preparation of Indole Containing Building Blocks for the Regiospecific Construction of Indole Appended Pyrazoles and Pyrroles