On May 21, 2007, Wang, Ping; Lee, Heeseob; Fukuda, Minoru; Seeberger, Peter H. published an article.Related Products of 130539-43-4 The title of the article was One-pot synthesis of a pentasaccharide with antibiotic activity against Helicobacter pylori. And the article contained the following:
A pentasaccharide that contains the α-1,4-GlcNAc mucin core two-branched O-glycan has been synthesized by a one-pot, two-step glycosylation strategy; this particular carbohydrate motif may provide protection against Helicobacter pylori induced pathologies since the synthetic pentasaccharide inhibits cholesterol α-glucosyltransferase (IC50 of 0.47 mM). The experimental process involved the reaction of Ethyl 2-deoxy-2-(1,3-dihydro-1,3-dioxo-2H-isoindol-2-yl)-1-thio-beta-D-glucopyranoside(cas: 130539-43-4).Related Products of 130539-43-4
The Article related to glycosylation glucosyltransferase inhibitor oligosaccharide synthesis antibacterial, cholesterol glucosyltransferase inhibitor oligosaccharide synthesis antibiotic helicobacter pylori antibacterial and other aspects.Related Products of 130539-43-4
Referemce:
Indole alkaloid derivatives as building blocks of natural products from Bacillus thuringiensis and Bacillus velezensis and their antibacterial and antifungal activity study,
Preparation of Indole Containing Building Blocks for the Regiospecific Construction of Indole Appended Pyrazoles and Pyrroles