The author of 《I2O5 promoted iodosulfenylation of indoles under metal-free conditions》 were Wang, Wangyang; Zhu, Fuyuan; Yan, Zhaohua; He, Mingchuang; Lin, Sen. And the article was published in Tetrahedron Letters in 2019. Related Products of 399-52-0 The author mentioned the following in the article:
A mild, efficient, and metal-free strategy to construct 2-iodo-3-arylthioindoles I (R = Cl, Me, Br, F, OMe; R1 = H, 4-Me, 5-OMe, 6-Br, etc.; R2 = H, Me) was developed via I2O5-promoted iodosulfenylation of indoles II utilizing simple, cheap and easily available thiophenols 4-RC6H4SH as sulfur sources. It is the first time that the iodothiolation difunctionalization of indoles II at C-2 and C-3 positions was accomplished with the formation of 2-iodo-3-arylthioindoles I in moderate to good yields. In the experiment, the researchers used 5-Fluoro-1H-indole(cas: 399-52-0Related Products of 399-52-0)
5-Fluoro-1H-indole(cas: 399-52-0) is a member of aromaticfluorinated building blocks. Fluorine-containing aromatics have been incorporated into crop-protection chemicals (herbicides, insecticides, fungicides). Liquid crystals, positron emission tomography, and imaging systems represent new areas where fluoroaromatics and fluoroheterocyclics have gained attention.Related Products of 399-52-0
Referemce:
Indole alkaloid derivatives as building blocks of natural products from Bacillus thuringiensis and Bacillus velezensis and their antibacterial and antifungal activity study,
Preparation of Indole Containing Building Blocks for the Regiospecific Construction of Indole Appended Pyrazoles and Pyrroles