An article Synthesis of the Madangamine Alkaloid Core by a C-C Bond Activation Cascade WOS:000480371600078 published article about 1ST ENANTIOSELECTIVE SYNTHESIS; UNIFIED TOTAL-SYNTHESIS; DIAZATRICYCLIC CORE; 3,3-DISUBSTITUTED OXINDOLES; TRICYCLIC CORE; CYANATION; EPOXIDES; ACIDS in [Eastwood, Matthew S.; Douglas, Christopher J.] Univ Minnesota Twin Cities, Dept Chem, 207 Pleast St SE, Minneapolis, MN 55455 USA in 2019.0, Cited 39.0. Formula: C7H8O. The Name is Benzyl Alcohol. Through research, I have a further understanding and discovery of 100-51-6
The diazatricyclic core of the madangamine alkaloids was synthesized from a densely functionalized cyclohexane derivative. An alkene and two cyanoformamide groups are used to form two new rings and a new quaternary stereocenter in a cascade reaction, which involves two Pd-catalyzed C-C bond activation steps. The synthesis of the cascade precursor involves an intramolecular Staudinger reaction of a vicinal diester that gives a [3.2.1]azabicyclooctane derivative, allowing the regioselective introduction of a monosubstituted alkene.
Formula: C7H8O. Welcome to talk about 100-51-6, If you have any questions, you can contact Eastwood, MS; Douglas, CJ or send Email.
Reference:
Indole alkaloid derivatives as building blocks of natural products from Bacillus thuringiensis and Bacillus velezensis and their antibacterial and antifungal activity study,
,Preparation of Indole Containing Building Blocks for the Regiospecific Construction of Indole Appended Pyrazoles and Pyrroles